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IHC - CD56

Immunohistochemistry (IHC) is a laboratory method used to visualize specific cellular components within a tissue sample. The IHC - CD56 test is a particular type of IHC test that targets the CD56 antigen, a protein found on the surface of certain immune cells.

CD56 is a neural cell adhesion molecule (NCAM) involved in cell adhesion and cell-to-cell communication. It's typically found on the surface of natural killer cells, a type of white blood cell involved in the body's immune response. In addition to its role in immune function, CD56 is also expressed in several types of tumors, including some forms of leukemia and lymphoma, neuroendocrine tumors, and small cell lung cancer.


  • Test NameIHC - CD56
  • Sample TypeTissue
  • Preparations RequiredThere are no specific instructions for this test. Follow your healthcare provider's advice.
  • Report Time3 days

What is the IHC - CD56 test?

The IHC - CD56 test is an immunohistochemical analysis that detects the presence of the CD56 antigen in a tissue sample. This test is often used to identify certain types of cancer cells.

Why do I need this test?

Your healthcare provider may order this test if they suspect you have a condition involving the immune system or certain types of cancers. The test can help identify the type of cells involved in the disease process, assisting in diagnosis and guiding treatment.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

A biopsy is performed to collect a tissue sample for the IHC - CD56 test. The biopsy method will depend on the location of the tissue to be sampled.

A positive test result means that the CD56 antigen was found in the tissue sample. This can suggest the presence of certain diseases, such as neuroendocrine tumors, natural killer cell lymphomas, and some forms of leukemia.

The turn around time for the IHC - CD56 test is typically 7 to 10 days, but this may vary depending on the laboratory.

The pain associated with the IHC - CD56 test is mainly related to the biopsy procedure used to obtain the tissue sample. Local or general anesthesia is usually used to minimize discomfort.

As with any procedure involving a biopsy, there are some risks, such as infection, bleeding, and an adverse reaction to anesthesia. Your healthcare provider will discuss these risks with you before the procedure.

Abnormal results may indicate the presence of a disease condition. Your healthcare provider will interpret your results in the context of your overall health and other diagnostic tests.

Generally, medications do not affect the results of the IHC - CD56 test. However, it's crucial to inform your healthcare provider of all medications you are taking.

There are no specific dietary restrictions before the IHC - CD56 test. However, if the test is part of a surgical procedure, you may be asked to fast beforehand. Follow the instructions provided by your healthcare provider.

The IHC - CD56 test is usually part of a panel of tests done to diagnose or monitor a disease condition. Additional tests may include other immunohistochemistry tests, cytogenetic analysis, and flow cytometry, among others.

The CD56 marker is used primarily to identify natural killer cells and certain types of T-cells. It's also present in a range of malignancies such as neuroendocrine tumors, small cell lung carcinoma, myeloma, and certain types of lymphomas and leukemias.

Your healthcare provider may order a repeat test if the results are inconclusive or if they need to monitor the progress of your treatment. The frequency of testing will depend on your individual health condition.

The quality of the tissue sample can affect the results of the IHC - CD56 test. Other factors could include technical issues with the staining process or interpretation of the results.

If your test result is abnormal, you may need to consult with a specialist. This could be an oncologist (cancer specialist), a hematologist (specialist in blood disorders), or an immunologist (specialist in immune system disorders), depending on your diagnosis.

The IHC - CD56 test is a powerful tool in the diagnostic process, offering valuable insights into the cellular composition of tissue samples. By identifying the presence of the CD56 antigen, healthcare providers can make more accurate diagnoses and provide tailored treatment plans. It's important to note that results should be interpreted in conjunction with other clinical findings and test results. If you have questions about this test or your results, it's always best to discuss them with your healthcare provider.

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