IHC - CD45-LCA - Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No specific preparation required before the test. It is a tissue biopsy, and the procedures will be done in a medical setting by a healthcare professional. The procedure involved in the test depends on the site from which the tissue sample is taken.

₹ 2000


The Immunohistochemistry (IHC) test for CD45, also known as the Leukocyte Common Antigen (LCA), is a specialized laboratory test that uses specific antibodies to identify certain proteins, called antigens, on cells from a tissue sample. This test is typically used in a pathology lab to help identify and classify lymphomas and leukemias.

The CD45 antigen is found on the surface of all white blood cells, including B cells, T cells, and granulocytes, making it a valuable diagnostic tool for diseases that involve these cells. The presence or absence of CD45 can provide crucial information for distinguishing between different types of lymphomas and leukemias, as well as other diseases.

The IHC CD45 test is not a routine test but is performed when a doctor suspects a patient has a lymphoproliferative disorder, like lymphoma or leukemia. The sample required for the test is usually obtained from a biopsy, in which a small piece of tissue is surgically removed for examination. The exact procedure depends on the location of the tissue being tested.

Test Name IHC - CD45/LCA
Sample Type Tissue biopsy
Preparations Required No specific preparation required before the test. It is a tissue biopsy, and the procedures will be done in a medical setting by a healthcare professional. The procedure involved in the test depends on the site from which the tissue sample is taken.
Report Time 3 days
Price in Hyderabad ₹ 2000

What does the IHC - CD45/LCA test measure?

The IHC - CD45/LCA test uses antibodies to detect the presence of the CD45 protein, also known as the Leukocyte Common Antigen (LCA), on cells in a tissue sample. The CD45 protein is found on all white blood cells, and its presence or absence can help diagnose certain types of lymphomas and leukemias.

What preparation is needed for the IHC - CD45/LCA test?

As this test is performed on a tissue sample, no specific patient preparation like fasting or medication restriction is necessary. The specifics of the biopsy procedure will depend on the location from which the tissue sample is taken.

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How is the biopsy for the IHC - CD45/LCA test performed?

The procedure for obtaining a biopsy depends on the location of the tissue to be tested. The area will be cleaned and numbed with a local anesthetic, then a small piece of tissue will be removed using a special tool. This might be done through a needle, incision, or surgical procedure. The sample is then sent to a lab for analysis.

Is there any risk associated with the biopsy procedure?

As with any procedure, there are risks involved with a biopsy. These may include pain, bleeding, infection, or damage to nearby structures. However, the benefits of obtaining a diagnosis often outweigh these risks. Discuss any concerns with your healthcare provider.

What does a positive result mean?

A positive result, meaning the CD45 protein was found, can indicate the presence of a lymphoproliferative disorder, such as a lymphoma or leukemia. However, the result of this test alone is not enough to confirm a diagnosis. Further testing is often needed to confirm the type and extent of the disease.

What does a negative result mean?

A negative result, meaning the CD45 protein was not found, can indicate that the tissue sample does not contain lymphoid cells or that the lymphoid cells in the sample do not express CD45. This result can help rule out certain types of lymphomas and leukemias.

Is this test done alone or with other tests?

The IHC - CD45/LCA test is usually done as part of a series of tests, including other immunohistochemistry tests, to diagnose lymphomas and leukemias. Your healthcare provider will use the results of all these tests together to make a diagnosis.

Can this test tell the difference between B-cell and T-cell lymphomas?

While the presence of CD45 can indicate a lymphoproliferative disorder, it cannot distinguish between B-cell and T-cell lymphomas. Other IHC tests are needed to identify the specific type of lymphoma.

How long does it take to get the results?

The time it takes to get results can vary, but it typically takes 5-7 days. This allows time for the tissue sample to be processed, the test to be run, and the results to be interpreted by a pathologist.

What factors can affect the test results?

The quality of the tissue sample can affect the accuracy of the test. If the sample is not sufficient or is not properly preserved, it may not be possible to detect the CD45 protein. Therefore, it is crucial that the biopsy is done correctly and the sample is properly handled and processed.

Who performs the biopsy for the IHC - CD45/LCA test?

The biopsy is usually performed by a healthcare professional who is experienced in the specific biopsy technique being used. This could be a surgeon, a radiologist, or another specialist, depending on the location of the tissue to be tested.

Is the IHC - CD45/LCA test painful?

The biopsy procedure may cause some discomfort, but local anesthesia is typically used to numb the area and minimize pain. You may feel pressure or a pinch when the sample is taken. After the procedure, there may be some soreness in the area where the biopsy was done.

Can the IHC - CD45/LCA test be done during pregnancy?

The decision to perform a biopsy during pregnancy depends on the potential benefits and risks. The healthcare provider will consider the urgency of the diagnosis and the possible risks to the mother and fetus.

Can I take my regular medications before the test?

Since the test involves a biopsy, you should discuss with your healthcare provider whether to continue taking your regular medications before the procedure, especially if you are taking any blood-thinning medications.

Can I drive myself home after the biopsy procedure?

Depending on the nature of the biopsy and whether sedation was used, you may need someone else to drive you home after the procedure. Discuss this with your healthcare provider before the day of your biopsy.

Immunohistochemistry tests like the IHC - CD45/LCA test are powerful tools that can help healthcare providers diagnose diseases that may be challenging to identify using other methods. If you have questions or concerns about this test, your healthcare provider is the best source of information for your specific situation.

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