The IHC - CD34 test is an immunohistochemical (IHC) procedure used in diagnostic pathology. It involves staining a tissue sample with a specific antibody, in this case, the CD34 antibody, which binds to the CD34 protein expressed in certain cells. This is a critical tool used in the diagnosis, prognosis, and monitoring of various medical conditions.
The CD34 protein is a cell surface glycoprotein expressed by various cell types, including endothelial cells (cells that line the blood vessels) and hematopoietic stem cells (cells in the bone marrow that give rise to all types of blood cells). The presence or absence of the CD34 protein can provide important clues about the type and nature of a disease or condition.
Test NameIHC - CD31
Sample TypeTissue Sample
Preparations RequiredNone. The test involves a biopsy procedure conducted by your healthcare provider.
Report Time3 days
What does the IHC - CD34 test involve?
The IHC - CD34 test involves a biopsy procedure where a small sample of tissue is taken from your body. The tissue is then prepared and stained with a CD34 antibody. If the CD34 protein is present in the cells of the tissue sample, the antibody will bind to it, indicating a positive result.
Why would I need an IHC - CD34 test?
The IHC - CD34 test can help diagnose a variety of conditions. It's commonly used to help identify tumors of endothelial or hematopoietic origin, including certain types of leukemia and lymphoma. The test can also provide valuable information about the prognosis of these conditions.
Home Sample Collection Process
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Book your convenient slot
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Sample Collection by Phlebotomist
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Reporting of the sample at lab
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Download Reports
Frequently Asked Questions
A positive IHC - CD34 test means that the CD34 protein was detected in the tissue sample. This result can indicate the presence of a tumor of endothelial or hematopoietic origin, but the exact interpretation will depend on the specific clinical context.
A negative IHC - CD34 test means that the CD34 protein was not detected in the tissue sample. This can rule out certain conditions, but the exact interpretation will depend on the specific clinical context.
No specific preparation is necessary for the IHC - CD34 test. The test involves a biopsy procedure, so your healthcare provider will give you detailed instructions about what to expect.
The IHC - CD34 test itself is not painful. However, the biopsy procedure used to obtain the tissue sample may cause some discomfort. Your healthcare provider will use local or general anesthesia to minimize any pain during the procedure.
The risks associated with the IHC - CD34 test are primarily related to the biopsy procedure. These can include pain, infection, and bleeding at the biopsy site. Your healthcare provider will discuss these risks with you and take steps to minimize them.
The turnaround time for the IHC - CD34 test is typically 3-5 days, but this can vary depending on the lab.
After getting the results of your IHC - CD34 test, you should schedule a follow-up appointment with your healthcare provider to discuss the results and any necessary next steps.
Yes, the IHC - CD34 test can be used to monitor the effectiveness of certain treatments, particularly in cases of hematopoietic or endothelial tumors.
Yes, the IHC - CD34 test is a reliable diagnostic tool when performed correctly. However, like all tests, its accuracy can be influenced by various factors, including the quality of the tissue sample and the specific procedures followed in the lab.
Yes, several factors can affect the results of your IHC - CD34 test. These include the quality of the tissue sample, the specific procedures followed in the lab, and the interpretation of the results by the pathologist.
Yes, the IHC - CD34 test is not only used in clinical diagnosis but also in research studies to understand the behavior and role of CD34-positive cells in various conditions.
CD34 is commonly expressed in endothelial cells, which line the blood vessels, and in hematopoietic stem cells, which give rise to all types of blood cells.
The IHC - CD34 test is often one of many tests used in the diagnosis and management of a condition. The other tests you might need will depend on the specific clinical context.
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