Immunohistochemistry (IHC) is a powerful tool used in the field of pathology and research to visualize the presence and distribution of specific proteins in tissue sections. IHC involves the use of antibodies that bind to these specific proteins in the tissue, which are then visualized by a detection system.
One such IHC test is the IHC - CD3 test, designed to detect the presence of the CD3 protein, a crucial component of the T-cell receptor complex. This protein is present on all mature T-cells, a type of white blood cell that plays a central role in immune response. The test is particularly helpful in identifying T-cell lymphomas, types of cancer that start in T-cells.
The IHC - CD3 test helps clinicians to determine the origin of lymphoid proliferations and classify lymphomas. This test is a standard part of the diagnostic and classification process for lymphoid neoplasms. In essence, it assists doctors to devise the best therapeutic strategy for the patient.
Test NameIHC - CD3
Sample TypeTissue
Preparations RequiredNo specific preparations are required for this test.
Report Time3 days
Why is the IHC - CD3 test important?
The IHC - CD3 test is important as it helps in the identification of T-cells in a tissue sample. This can be crucial for diagnosing T-cell lymphomas and other conditions affecting the immune system.
Is fasting required for the IHC - CD3 test?
No, fasting is not required for the IHC - CD3 test.
Home Sample Collection Process
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Book your convenient slot
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Sample Collection by Phlebotomist
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Reporting of the sample at lab
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Download Reports
Frequently Asked Questions
The sample for the IHC - CD3 test is a tissue sample, usually obtained through a biopsy. The biopsy procedure will be done by a trained healthcare professional.
The IHC - CD3 test measures the presence of the CD3 protein in a tissue sample. The CD3 protein is part of the T-cell receptor complex and is found on all mature T-cells.
In a healthy tissue sample, the presence of CD3 indicates the presence of T-cells. However, the normal values can vary depending on the specific area of the body from which the sample is taken.
The frequency of the IHC - CD3 test will depend on your medical condition and your doctor's recommendations.
There are no specific precautions for the IHC - CD3 test. However, you should inform your doctor about any medications or supplements you are taking, as they might interfere with the test results.
The levels of CD3 can be affected by various factors. Non-modifiable factors include genetic predispositions to certain immune conditions. Modifiable factors can include infections, autoimmune conditions, or specific medications that affect the immune system.
If your test results are abnormal, you should consult a hematologist, an oncologist, or an immunologist, depending on your symptoms and the nature of the abnormality.
The IHC - CD3 test itself is not painful. However, the biopsy procedure used to collect the tissue sample can cause some discomfort. Your healthcare provider will take measures to minimize any discomfort.
The results of the IHC - CD3 test can help identify whether the tissue sample contains T-cells, and if so, how many. This can be useful in diagnosing T-cell lymphomas and other immune conditions.
Yes, certain medications can affect the immune system and may influence the results of the IHC - CD3 test. It's important to inform your doctor about any medications you're taking.
Yes, in some cases, doctors use the IHC - CD3 test to monitor how well a treatment for certain cancers or immune disorders is working.
No, there is no age limit for the IHC - CD3 test. The test can be performed on individuals of all ages, based on medical necessity.
Coverage for the IHC - CD3 test depends on your insurance plan. It's best to check with your insurance provider for details. The IHC - CD3 test is a valuable tool that aids in the diagnosis and treatment of several conditions, particularly those involving the immune system. With minimal preparation required and no major risks associated, it's a safe procedure that provides essential information to your healthcare provider. As with any diagnostic test, understanding what it entails helps you to be an active participant in your healthcare journey.
The IHC - CD3 test is highly accurate in detecting the CD3 protein in tissue samples. However, the interpretation of the test may sometimes be complex and requires a skilled pathologist.
Yes, the IHC - CD3 test can be performed during pregnancy if needed. However, the biopsy procedure to obtain the tissue sample may have associated risks. Please discuss with your healthcare provider.
A18: Yes, certain infections can stimulate the immune response, increasing the number of T-cells and possibly affecting the results of the IHC - CD3 test.
A19: CD3 levels can't be directly influenced by diet or lifestyle changes as they reflect the body's immune response. However, maintaining overall good health and managing any underlying conditions can help support your immune system.
The turnaround time for the IHC - CD3 test is typically between 3-5 days, but it may vary depending on the laboratory.
After the test, your doctor will discuss the results with you and determine the next steps based on the findings. This may include further tests or starting a treatment plan if necessary.
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