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(IHC - CD2)

Immunohistochemistry (IHC) refers to a laboratory technique used to visualize proteins in tissue sections. The IHC - CD2 test specifically identifies the presence of the CD2 antigen in a tissue sample. CD2 is a cell adhesion molecule found on the surface of T cells and natural killer cells. It plays crucial roles in facilitating cell-cell interactions during immune responses.

In a clinical context, this test is valuable in distinguishing T cell lymphomas from other lymphoid malignancies, which assists in the diagnosis and staging of certain cancers. However, it is not a standalone diagnostic tool. The results must be interpreted in conjunction with other clinical and diagnostic information.


  • Test Name(IHC - CD2)
  • Sample TypeTissue
  • Preparations RequiredNo special preparation is required for this test.
  • Report Time3 days

What is the purpose of the IHC - CD2 test?

The IHC - CD2 test is used to detect the presence of the CD2 antigen, commonly found on the surface of T cells and natural killer cells. It helps in distinguishing T cell lymphomas from other lymphoid malignancies.

How is the test performed?

The test involves applying antibodies specific to the CD2 antigen on a section of tissue. If CD2 is present, it will bind to the antibodies and can be visualized under a microscope.

Home Sample Collection Process

1
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2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Frequently Asked Questions

This test requires a tissue sample, often obtained through a biopsy.

No special preparation is required for the IHC - CD2 test.

The typical turn-around time for this test is 1 to 3 days, though this may vary depending on the laboratory.

A positive result indicates the presence of the CD2 antigen in the tissue sample, which may suggest a T cell lymphoma. However, the test results need to be interpreted along with other clinical and diagnostic information.

Yes, the IHC - CD2 test can help distinguish T cell lymphomas from other lymphoid malignancies.

The decision to perform this test depends on various factors, including the patient's clinical symptoms, medical history, and other diagnostic test results.

The IHC - CD2 test is not a standalone diagnostic tool. The results must be interpreted in the context of other clinical and diagnostic information.

The IHC - CD2 test does not directly provide information about the prognosis or response to treatment. However, the results can help guide the choice of treatment strategies by identifying the type of lymphoma.

The absence of CD2 does not necessarily mean that the patient doesn't have lymphoma. Some lymphomas do not express CD2, and other tests may be needed to confirm a diagnosis.

While the IHC - CD2 test can be useful in the initial diagnosis and classification of lymphomas, it is not typically used for monitoring disease progress or treatment effectiveness.

The test itself has no side effects, but the biopsy procedure used to obtain the tissue sample may have risks, such as infectionor bleeding.

Yes, several other tests, including other immunohistochemistry tests, flow cytometry, and molecular tests, can also be used to diagnose and classify lymphomas.

The quality of the tissue sample and the technical process of performing the test can influence the results. It's crucial that the test is conducted in a specialized laboratory to ensure accuracy.

No, not all labs offer this test as it requires specialized equipment and expertise. It's crucial to ensure that the test is performed at an accredited laboratory that adheres to stringent quality standards.

No, this test specifically requires a tissue sample, typically obtained via biopsy, to assess the presence of the CD2 antigen.

The interpretation of IHC - CD2 test results should be performed by a healthcare professional. They will consider these results along with other diagnostic tests and clinical findings to provide a comprehensive diagnosis.

While the CD2 antigen is particularly useful in identifying T-cell lymphomas, it can also be useful in the study of other diseases that affect T cells, including autoimmune diseases and immunodeficiency disorders.

CD2 is a cell adhesion molecule found on the surface of T cells and natural killer cells. It plays crucial roles in facilitating cell-cell interactions during immune responses.

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