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IHC - Actin - Smooth muscle (SMA)

IHC - Actin - Smooth muscle (SMA)

The field of pathology and diagnostics has seen significant advancements in recent years, and one such progress is the use of Immunohistochemistry (IHC). The IHC - Actin - Smooth Muscle (SMA) test, specifically, provides crucial information that aids in the diagnosis of several conditions, predominantly concerning smooth muscle tumors and connective tissue disorders.

Smooth muscle actin (SMA) is a protein found in smooth muscle cells, which are the cells that make up the involuntary muscles in your body — these muscles control functions like the flow of blood through your veins and food through your digestive tract. By using specific antibodies that bind to the SMA protein, the IHC - Actin - Smooth Muscle test can identify the presence and distribution of smooth muscle cells in a tissue sample, thereby helping to identify certain types of tumors and tissue abnormalities.


  • Test NameIHC - Actin - Smooth muscle (SMA)
  • Sample TypeTissue
  • Preparations RequiredNone
  • Report Time3 days

What is the importance of getting the IHC - Actin - Smooth Muscle (SMA) test done?

The IHC - Actin - Smooth Muscle (SMA) test is a crucial diagnostic tool used to confirm the diagnosis of conditions involving smooth muscle cells, including various types of tumors. It helps in differentiating between tumors that originated in the smooth muscle (leiomyomas and leiomyosarcomas) and those that didn't. An accurate diagnosis is necessary for determining the most effective treatment approach.

Is fasting required for the IHC - Actin - Smooth Muscle (SMA) test?

No, fasting is not required for the IHC - Actin - Smooth Muscle (SMA) test. This test is performed on a tissue sample obtained from a biopsy or surgical procedure.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

No specific preparation is needed for this test. However, if you are having a biopsy or surgical procedure to obtain the tissue sample, your healthcare provider will give you specific instructions to prepare for that procedure.

Your doctor may order the IHC - Actin - Smooth Muscle (SMA) test if they suspect a condition that involves smooth muscle cells, particularly if they suspect a smooth muscle tumor or if they need to differentiate a smooth muscle tumor from another type of tumor. The test can also be used to track the progress of a known condition or to monitor the effectiveness of treatment.

The IHC - Actin - Smooth Muscle (SMA) test identifies the presence and distribution of smooth muscle actin (SMA) in a tissue sample. This information can help diagnose conditions involving smooth muscle cells, particularly tumors that originate in the smooth muscle.

The frequency of the IHC - Actin - Smooth Muscle (SMA) test depends on your individual medical condition. If you are being treated for a condition involving smooth muscle cells, your doctor may order this test periodically to monitor your response to treatment. Your healthcare provider can provide guidance based on your specific situation.

There are no typical "normal" values for the IHC - Actin - Smooth Muscle (SMA) test. The test is qualitative and indicates the presence or absence of smooth muscle actin (SMA) in the tissue sample. The results need to be interpreted by a qualified medical professional in the context of your symptoms, medical history, and other test results.

There are no specific precautions to be taken for the IHC - Actin - Smooth Muscle (SMA) test itself. However, if you're having a biopsy or surgery to collect the tissue sample, your healthcare provider will give you specific instructions about the preparation for that procedure.

The levels of SMA detected in the IHC - Actin - Smooth Muscle (SMA) test can be affected by various factors. The type, stage, and location of a tumor, as well as any treatments you might be receiving, can influence the amount of SMA in the tissue sample.

If your test results are abnormal, you should consult with your primary healthcare provider or a specialist who can interpret the results in the context of your overall health and medical history. This might be a pathologist, an oncologist, or another specialist, depending on your specific circumstances.

The IHC - Actin - Smooth Muscle (SMA) test is a valuable tool in modern medicine's toolkit. By providing information about the presence and distribution of smooth muscle cells, it aids healthcare professionals in diagnosing and managing various conditions, enhancing the precision of medical treatment. Understanding your diagnostic tests is a crucial aspect of your healthcare journey, empowering you to make informed decisions about your health. As always, maintaining an open dialogue with your healthcare provider is essential for the best outcomes.

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