IDH 1_2 Mutation Analysis Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No fasting is required for this test. You can eat and drink normally before the test.

₹ 7700


IDH 1&2 Mutation Analysis is a genetic test used primarily in the diagnosis and management of certain types of cancers, notably brain tumors and acute myeloid leukemia (AML). The test detects mutations in the IDH1 and IDH2 genes, which are often associated with these malignancies.

IDH1 and IDH2 are genes that code for isocitrate dehydrogenase enzymes, which are involved in cellular metabolism. When functioning normally, these enzymes help to break down nutrients and generate energy for cells. However, mutations in these genes can cause the enzymes to function abnormally and lead to the development of cancer.

Test Name IDH 1&2 Mutation Analysis
Sample Type Paraffin embedded tissue blocks
Preparations Required No fasting is required for this test. You can eat and drink normally before the test.
Report Time 12 days
Price in Hyderabad ₹ 7700

Why is IDH 1&2 Mutation Analysis important?

This test is crucial because it helps in diagnosing certain types of cancers, notably gliomas (a type of brain tumor) and acute myeloid leukemia (AML). The presence of IDH1 or IDH2 mutations can influence the treatment approach and overall prognosis.

Is fasting required for the IDH 1&2 Mutation Analysis test?

No, fasting is not required for this test. You can eat and drink normally before the test.

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What is the preparation for this test?

There is no specific preparation required for this test. You can maintain your usual diet and activities.

When should I get this test?

If you have symptoms of a brain tumor or acute myeloid leukemia (AML) or if you've already been diagnosed with these conditions, your doctor might recommend an IDH 1&2 Mutation Analysis.

What does this test measure?

This test measures the presence of mutations in the IDH1 and IDH2 genes. These mutations are associated with certain types of cancers, including gliomas and AML.

How often should this test be done?

The frequency of this test largely depends on your doctor’s recommendation, based on your health condition and response to treatment.

What are the normal values?

The "normal" result for this test is the absence of mutations in the IDH1 and IDH2 genes.

What precautions should I take?

There are no specific precautions necessary for this test. However, it's important to discuss all your symptoms, medical history, and any medications you're taking with your healthcare provider.

Which factors can affect the levels of IDH 1&2?

Modifiable factors that can influence the results include diet and lifestyle. Non-modifiable factors include age, sex, and genetic predisposition.

Which doctor should I consult if the results are abnormal?

You should consult with a oncologist or a hematologist if your results are abnormal.

Can the IDH 1&2 Mutation Analysis test detect all types of cancer?

No, IDH 1&2 Mutation Analysis test specifically helps in diagnosing certain types of cancers, notably gliomas and AML.

Is the IDH 1&2 Mutation Analysis test painful?

The test involves a blood draw, which can cause slight discomfort. However, any pain should be minimal and short-lived.

Can I take medications before the IDH 1&2 Mutation Analysis test?

Yes, you can take your regular medications unless instructed otherwise by your doctor. Be sure to inform your healthcare provider about all the medications and supplements you are taking.

Can the results of the IDH 1&2 Mutation Analysis test influence treatment decisions?

Yes, the results of the IDH 1&2 Mutation Analysis test can significantly influence treatment decisions. For example, some therapies are specifically designed to target tumors with these mutations.

How is the sample collected for the IDH 1&2 Mutation Analysis test?

The sample can be collected through a blood draw or a tissue biopsy, depending on your condition and your doctor's recommendation.

In conclusion, the IDH 1&2 Mutation Analysis test is a valuable diagnostic tool that plays a crucial role in the diagnosis and management of certain cancers. However, it is essential to discuss your test results with your healthcare provider to understand what they mean in the context of your overall health status.

What are the risks associated with IDH 1&2 Mutation Analysis?

Like any genetic test, the IDH 1&2 Mutation Analysis carries a small risk of psychological stress or anxiety. Additionally, if a blood sample is used, minor risks such as slight pain, bruising, or infection at the injection site may occur.

Can the IDH 1&2 Mutation Analysis be used to monitor treatment progress?

Yes, the test can be repeated over time to assess the effectiveness of treatment. This is particularly useful in cases where targeted therapy is being used.

What's the difference between IDH1 and IDH2 mutations?

Both IDH1 and IDH2 mutations involve changes in the genes that encode isocitrate dehydrogenase enzymes, which are involved in cellular metabolism. The difference lies in the location of the genes: IDH1 is located in the cytoplasm and peroxisomes, while IDH2 is located in the mitochondria. Both mutations can contribute to cancer development.

What is the connection between IDH mutations and prognosis in cancer patients?

IDH mutations, particularly in gliomas and AML, have been associated with a better prognosis compared to similar diseases without these mutations. However, the exact outcome can depend on various factors, including the specific type of mutation, the stage of the disease, and the patient's overall health.

Can lifestyle changes impact the result of the IDH 1&2 Mutation Analysis?

No. IDH1 and IDH2 are gene mutations, and gene mutations are generally non-modifiable. They cannot be influenced by lifestyle changes.

Is the IDH 1&2 Mutation Analysis test available worldwide?

Yes, the test is available in most advanced diagnostic laboratories worldwide. However, availability can vary depending on the country and healthcare system.

How reliable is the IDH 1&2 Mutation Analysis?

The test is highly reliable when performed in an accredited laboratory by trained professionals. However, no test is 100% accurate. There's a small chance of false-positive or false-negative results.

Can a negative IDH 1&2 Mutation Analysis test mean that I don't have cancer?

No, a negative result only means that IDH1 or IDH2 mutations were not detected. Other genetic or environmental factors might be involved in cancer development. Therefore, further testing might be needed to confirm or rule out a diagnosis.

How soon can I expect the results of the IDH 1&2 Mutation Analysis test?

The turnaround time can vary depending on the laboratory. Typically, results are available within 1-2 weeks after the sample collection.

Understanding your IDH 1&2 Mutation Analysis test results can provide valuable insights into your health condition, and guide therapeutic strategies. Always discuss the results with your healthcare provider for a comprehensive interpretation and the next steps in your care.

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