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Lab Test

Hu Antibody - (Against neuronal antigen in Paraneoplastic syndromes)

Hu antibodies are proteins produced by the immune system in response to an underlying cancer. They react against normal tissues in the body, particularly those in the nervous system. Testing for Hu antibodies is an essential part of diagnosing paraneoplastic syndromes, a group of conditions that arise as a result of cancer but are not due to the local presence of cancer cells.


  • Test NameHu Antibody - (Against neuronal antigen in Paraneoplastic syndromes)
  • Sample TypeBlood
  • Preparations RequiredNone
  • Report Time24 hours

Paraneoplastic syndromes often manifest before the cancer that causes them is detected. The symptoms can be diverse and affect various body systems, often making them difficult to diagnose. One particular group of these syndromes, known as paraneoplastic neurological syndromes (PNS), are associated with neuronal antibodies like Hu. PNS can affect any part of the nervous system and often lead to neurological symptoms like memory loss, balance issues or difficulty walking.

Hu antibodies are most often associated with small cell lung cancer (SCLC), but they can also occur with other cancers. If Hu antibodies are detected in a patient's blood, it may be an early warning sign of a hidden cancer, prompting further investigation. The test for Hu antibodies involves a simple blood draw and is typically completed within a week.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Frequently Asked Questions

Hu antibodies are proteins produced by the immune system. They are often found in patients with certain types of cancer and can cause damage to the nervous system, leading to a group of conditions known as paraneoplastic syndromes.

This test is done to detect the presence of Hu antibodies in the blood. These antibodies may be an early sign of a hidden cancer, most commonly small cell lung cancer. Detecting them can help doctors diagnose the underlying cancer and begin treatment as early as possible.

The test involves a simple blood draw. The blood sample is then sent to a laboratory, where it is tested for the presence of Hu antibodies.

No, fasting is not required for this test.

No specific preparation is needed for this test.

This test is typically ordered when a person has neurological symptoms that can't be explained by other diagnoses. If you are experiencing unexplained neurological symptoms, your doctor may order this test.

This test measures the presence of Hu antibodies in the blood. These antibodies can cause damage to the nervous system and may be a sign of a hidden cancer.

The frequency of testing depends on your symptoms and your doctor's recommendations. If you have been diagnosed with a paraneoplastic syndrome, your doctor may order regular testing to monitor your condition.

Normal values for this test are negative, meaning no Hu antibodies are detected in the blood.

No specific precautions are needed before this test. However, it's always a good idea to discuss any medications or supplements you're taking with your doctor, as these could potentially interfere with the results.

The presence of Hu antibodies in the blood is typically a sign of an underlying cancer. Factors that could affect the levels of these antibodies include the size and type of the cancer, as well as the effectiveness of any ongoing cancer treatment.

If your test results are positive for Hu antibodies, it's important to follow up with your doctor. They will likely order additional tests to determine the underlying cause and develop an appropriate treatment plan.

No, this test cannot be done at home. It requires a blood sample to be taken by a healthcare professional and analyzed in a laboratory.

Most insurance plans cover the cost of diagnostic tests like the Hu antibody test, but it's always a good idea to check with your insurance provider to be sure.

Hu antibodies are typically not found in healthy individuals. Their presence is usually indicative of an underlying cancer, particularly small cell lung cancer.

Paraneoplastic syndromes can cause a wide range of symptoms, depending on which part of the nervous system is affected. Common symptoms include difficulty walking, memory loss, vision problems, and seizures.

Treatment of paraneoplastic syndromes typically involves treating the underlying cancer. Additional treatments, like immunosuppressive drugs, may also be used to help manage symptoms.

While Hu antibodies are most commonly associated with small cell lung cancer, they can also be associated with other types of cancer. If Hu antibodies are detected, additional tests will likely be needed to determine the type and location of the cancer.

The production of Hu antibodies is typically a response to an underlying cancer. Therefore, cancer prevention strategies, such as not smoking, maintaining a healthy weight, and getting regular check-ups, can help prevent their production.

This test is highly accurate in detecting Hu antibodies in the blood. However, a positive result doesn't confirm the presence of cancer, and further tests will be needed to make a definitive diagnosis.

Hu Antibody - (Against neuronal antigen in Paraneoplastic syndromes)
₹ 5500
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