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Lab Test

HLA - KIR (killer cell immunoglobulin-like receptors) typing

Killer cell immunoglobulin-like receptors (KIRs) are proteins found on the surface of natural killer (NK) cells, a type of white blood cell. KIR typing is a laboratory test used to identify the genetic variants of KIRs. These receptors play a vital role in the immune system, specifically in the body's innate immune response.


  • Profile Name: HLA - KIR (killer cell immunoglobulin-like receptors) typing
  • Sample Type: Buccal swab
  • Preparations Required: None, you may follow your normal diet and activities unless otherwise specified by your doctor.
  • Report Time: 12 Days

There is a diverse range of KIR genes, and each person has a unique combination, which influences the activity of their NK cells. Understanding the KIR genotypes is important in some contexts, such as transplantation, as it can help predict the success of the procedure and the risk of graft versus host disease (GvHD). It can also play a role in understanding susceptibility to some autoimmune and infectious diseases.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

The HLA - KIR Typing test is done to identify the genetic variants of KIRs on NK cells. The information from the test is helpful in predicting the success of transplants, understanding the risk of certain autoimmune diseases, and infectious diseases.

The test requires a blood sample. The sample is analyzed in a laboratory where the DNA is extracted and used in a procedure called polymerase chain reaction (PCR) to determine your KIR genotype.

The test involves a standard blood draw, which may cause a slight pricking sensation and minor discomfort. However, it is generally well tolerated.

There are no specific preparations needed for the HLA - KIR Typing test. It's recommended to maintain your normal diet and routine unless your doctor advises differently.

The results of your HLA - KIR Typing test will typically be sent to the doctor who requested the test. They will then discuss the results with you and explain what they mean in the context of your health.

The test involves a routine blood draw, which carries minimal risks, such as slight pain or bruising at the injection site, lightheadedness, or, in rare cases, infection.

Your KIR genotype is simply a part of your genetic makeup and isn't inherently good or bad. However, certain KIR genotypes can affect your immune system's function and may make you more susceptible to certain diseases or impact the success rate of transplants.

Yes, the HLA - KIR Typing test is a non-invasive blood test and can be taken even if you're pregnant. If you're pregnant and considering this test, please consult with your doctor.

HLA (Human Leukocyte Antigen) typing and KIR typing are both used to understand an individual's immune system better. However, while HLA molecules are present on nearly all cells in the body, KIRs are specifically found on NK cells.

In transplantation, particularly bone marrow or stem cell transplantation, matching the donor and recipient's HLA type is crucial. Additionally, KIR typing can provide further insight into how the recipient's immune system may interact with the transplanted cells. It helps predict the success of the transplant and the risk of GvHD.

The turnaround time can vary, but generally, you can expect your results within 1-2 weeks after the sample is collected.

No, the HLA - KIR Typing test by itself doesn't diagnose diseases. It provides information about your immune system that can help your healthcare provider understand your risk for certain conditions or predict the success of transplants.

No, the HLA - KIR Typing test requires a blood sample to be taken by a healthcare professional and should be performed in a certified laboratory.

Yes, you may eat and drink normally before the test unless your doctor specifies otherwise.

Having a rare KIR genotype is not necessarily a cause for concern. However, it could influence your immune system's function and might be a factor in susceptibility to certain conditions or the success rate of transplants. Your doctor can explain what your specific KIR genotype means for your health.

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