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HLA Celiac Disease

HLA Celiac Disease

The HLA Celiac Disease DR-DQb1-DQA1 test is a genetic test used in the diagnostic process of celiac disease. Celiac disease is an autoimmune disorder where the ingestion of gluten leads to damage in the small intestine. Certain variations of the Human Leukocyte Antigen (HLA) genes, namely HLA-DQ2 and HLA-DQ8, are associated with an increased risk of developing celiac disease. This test is designed to identify these genetic variants


  • Test Name HLA Celiac Disease DR-DQb1-DQA1
  • Sample Type Blood
  • Preparations Required
  • Report Time

While the presence of HLA-DQ2 or HLA-DQ8 does not confirm a diagnosis of celiac disease, their absence essentially rules it out. Thus, this genetic test is particularly helpful in cases where the diagnosis is uncertain, or in screening first-degree relatives of individuals with celiac disease.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

It's a genetic test that identifies specific gene variants associated with an increased risk of celiac disease.

This test is used to help diagnose celiac disease, especially in cases where the diagnosis is uncertain, or to screen family members of individuals with the disease.

The test is performed on a blood sample taken from a vein in your arm.

A positive result means that you carry the gene variants associated with an increased risk of celiac disease. However, it doesn't confirm that you have the disease.

A negative result means you don't carry the HLA-DQ2 or HLA-DQ8 gene variants, and it's unlikely that you have celiac disease.

The test is highly accurate at identifying the HLA-DQ2 and HLA-DQ8 gene variants, but it's not a definitive test for celiac disease.

Yes, children can undergo this test, especially if they have symptoms of celiac disease or a family history of the condition.

The test involves a routine blood draw, which may cause slight pain, bruising, or bleeding at the site of needle insertion.

Yes, you can eat and drink normally before the test. There are no special preparations needed.

Not necessarily. A positive result means you have the gene variants associated with celiac disease, but it doesn't confirm that you have the disease.

A negative result means it's highly unlikely you'll develop celiac disease.

Yes, if you have a positive result, your first-degree relatives (parents, siblings, children) may also want to consider testing as they have a higher risk of also having the disease.

The results are usually available within 7-10 days.

No, you don't need to stop taking your medications before the test. However, it's always a good idea to inform your doctor about all the medications you're taking.

No, this test is specific for celiac disease. Other gluten-related disorders require different tests for diagnosis.

No, this test is specific for celiac disease. However, individuals with celiac disease are at a higher risk of developing other autoimmune disorders, and this test may indirectly indicate a predisposition to these other conditions.

No, while this test is highly useful in diagnosing celiac disease, it doesn't replace other diagnostic tests like antibody testing and intestinal biopsy, which are used to confirm the diagnosis.

Yes, HLA Celiac Disease DR-DQb1-DQA1 test can be safely performed during pregnancy. If you are pregnant and have symptoms of celiac disease or a family history, talk to your doctor about the necessity of this test.

Currently, there is no cure for celiac disease, but the condition can be managed effectively by following a strict gluten-free diet, which helps to heal the gut and reduce symptoms.

No, this test requires a blood sample to be drawn by a healthcare professional and needs to be processed in a specialized laboratory.

Coverage can vary widely, so it's recommended that you check with your insurance provider to understand if and how much of the cost they cover.

Genetic counselling is not mandatory but is beneficial, especially if the test identifies the presence of gene variants associated with celiac disease.

Not necessarily. Having the gene variants doesn't mean you have or will develop celiac disease. It's best to discuss this with your doctor.

The detection of gene variants should be consistent across labs. However, the interpretation of results can vary, making it crucial to discuss your results with your healthcare provider or a genetic counsellor.

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