HLA - B8 Test - Human Leukocyte Antigen | Sprint Diagnostics Hyderabad

Patient Preparing : No special preparation is needed for this test. Continue with your regular diet and medications unless instructed otherwise by your healthcare provider.

₹ 5500


The HLA-B8 test is a diagnostic procedure that looks at the human leukocyte antigen (HLA) system in your body, specifically the B8 variant. The HLA system is crucial for the immune system's ability to differentiate the body's own proteins from those of potentially harmful entities, like bacteria and viruses.

The HLA-B8 variant has been found to be associated with certain autoimmune diseases such as Myasthenia gravis, celiac disease, and certain types of lupus. The HLA - B8 test identifies this specific variant and can be used in the diagnosis and risk prediction of these conditions. The test is performed on a sample of your blood and employs a technique called PCR (polymerase chain reaction) to amplify and detect the specific DNA sequence associated with the HLA-B8 variant.

Test Name HLA - B8
Sample Type Blood
Preparations Required No special preparation is needed for this test. Continue with your regular diet and medications unless instructed otherwise by your healthcare provider.
Report Time 3 days
Price in Hyderabad ₹ 5500

Why might I need an HLA - B8 test?

If you have symptoms suggestive of an autoimmune condition, or if you have a family history of autoimmune diseases, your healthcare provider might recommend the HLA - B8 test to aid in diagnosis or assess your risk.

How is the HLA - B8 test performed?

HLA - B8 test is performed on a sample of your blood. The DNA from your blood cells is analyzed to identify the presence of the HLA-B8 variant.

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What should I do to prepare for this test?

Generally, no special preparation is needed for this test. You can maintain your normal diet, water intake, and medication schedule unless your healthcare provider advises otherwise.

How will I interpret my test results?

The presence of the HLA-B8 variant in your DNA might indicate an increased risk for certain autoimmune conditions. However, it's important to remember that not everyone with this variant will develop these diseases. Your healthcare provider will help you understand what your results mean for your health.

What are the implications of a positive HLA-B8 test result?

A positive test result doesn't mean you have an autoimmune disease, but it can suggest a higher risk. The test should be considered as part of a broader diagnostic process, taking into account your symptoms, medical history, and other test results.

Can the HLA-B8 test be used to monitor disease progression?

The HLA-B8 test is primarily used for diagnostic and risk assessment purposes. Other tests and clinical evaluations are typically used to monitor disease progression.

Is the HLA-B8 test suitable for everyone?

This test may not be appropriate for everyone. It's typically recommended for individuals with symptoms of an autoimmune disease or a family history of such conditions. Always discuss with your healthcare provider to determine if this test is suitable for you.

Can diet and lifestyle influence the HLA-B8 test result?

Your HLA-B8 status is determined by your genes, and it doesn't change based on your diet or lifestyle. However, lifestyle factors can influence the onset and progression of autoimmune diseases.

Is the HLA-B8 test the only test used to diagnose autoimmune conditions?

No, the HLA-B8 test is one of many tools healthcare providers use to diagnose these conditions. Other tests may include antibody tests, imaging studies, and biopsy, depending on the specific condition suspected.

Does a negative test result mean I will never develop an autoimmune disease?

No, a negative result does not guarantee you will not develop an autoimmune disease. It simply means you do not carry the HLA-B8 variant, which is associated with a higher risk of certain conditions. Autoimmune diseases are complex and can be influenced by many other genetic and environmental factors.

Can HLA-B8 testing be performed on children?

Yes, HLA-B8 testing can be performed on individuals of any age, including children. In some cases, this test may be recommended for children who have a family history of autoimmune diseases or are exhibiting symptoms suggestive of these conditions.

How reliable is the HLA-B8 test?

The HLA-B8 test is highly reliable for identifying the presence or absence of the HLA-B8 variant. However, it's important to understand that carrying this variant does not definitively mean you will develop an autoimmune disease, and not carrying it does not mean you're immune from these conditions.

Can this test predict the severity of an autoimmune disease?

No, the HLA-B8 test does not provide information about disease severity or progression. It only identifies the presence of a specific genetic variant that is associated with certain autoimmune conditions.

Is genetic counseling recommended before or after undergoing the HLA-B8 test?

Genetic counseling can be beneficial both before and after genetic testing. Prior to testing, a counselor can help you understand the benefits, risks, and potential outcomes of the test. After testing, they can assist in interpreting the results and discussing next steps.

Does having the HLA-B8 variant affect my chances of passing an autoimmune disease to my children?

If you have the HLA-B8 variant, there is a chance you could pass it to your children. However, this does not guarantee they will develop an autoimmune disease. These diseases are usually the result of a combination of genetic and environmental factors, and the presence of HLA-B8 is just one aspect of risk.

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