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HIV-1 Drug Resistance – Genotypic

HIV-1 Drug Resistance – Genotypic

The HIV-1 Drug Resistance - Genotypic test is a critical diagnostic tool used to identify genetic mutations in the HIV-1 virus that can make it resistant to certain antiretroviral drugs. The test is typically recommended for people diagnosed with HIV-1, particularly those who are about to start therapy, those for whom therapy is not working, and those experiencing a viral rebound after a period of viral suppression.

  • Test Name HIV-1 Drug Resistance – Genotypic
  • Sample Type Blood
  • Preparations Required None
  • Report Time 2 days

HIV-1 is the most common and aggressive type of HIV. It mutates rapidly, and these mutations can cause the virus to become resistant to some antiretroviral drugs. This can hinder the effectiveness of treatment and contribute to treatment failure. By identifying these mutations, the genotypic resistance test can guide clinicians in selecting the most effective treatment regimen, helping to control the patient's viral load, prevent the progression of HIV to AIDS, and reduce the transmission of the virus.

Home Sample Collection Process

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Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
Reporting of the sample at lab
Reporting of the sample at lab
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Download Reports
Frequently Asked Questions

The test is crucial for the effective management of HIV-1 as it helps identify which antiretroviral drugs the virus is resistant to. This information allows healthcare providers to personalize treatment plans for patients, increasing the chances of successful viral suppression.

No, fasting is not necessary for this test.

No special preparation is required before the test.

The test is generally recommended when you are about to start antiretroviral therapy, if your therapy is not suppressing your viral load, or if your viral load increases after a period of suppression.

The test identifies genetic mutations in HIV-1 that confer resistance to certain antiretroviral drugs.

The frequency of testing depends on individual circumstances, including changes in viral load and the effectiveness of current treatment.

The test results are not given in terms of normal or abnormal but provide a list of antiretroviral drugs to which the virus is resistant.

Standard precautions related to blood tests apply. You should inform your healthcare provider about all the medications you are currently taking.

The stage of infection, the effectiveness of current therapy, and the presence of co-infections can affect test results.

If the test indicates drug resistance, you should consult your healthcare provider, who may refer you to a specialist in infectious diseases or HIV/AIDS care.

Once drug resistance develops, it usually persists, even if the drug is discontinued. This is why selecting the right regimen based on resistance testing is crucial.

Adherence to the prescribed antiretroviral regimen is the best way to prevent drug resistance. This includes taking the drugs exactly as prescribed, at the correct time, and not missing doses.

The test involves a standard blood draw, which may cause some discomfort and minor bruising at the site of the needle insertion but should not be significantly painful.

The turn-around time for the test results is typically 1-2 weeks.

No, the test requires a blood sample that must be collected by a healthcare professional in a clinical setting.

Yes, other medications can affect the results of the test. Always inform your healthcare provider about all medications and supplements you are taking.

The test is highly reliable when performed in a certified laboratory by trained professionals.

In rare cases, HIV-1 may become multi-drug resistant, but with the large number of antiretroviral drugs available, it is generally possible to find an effective regimen.

The blood sample is analyzed using genotypic resistance testing, which identifies the presence of specific genetic mutations in the virus that confer resistance to antiretroviral drugs.

Yes, with effective antiretroviral therapy, regular monitoring, and lifestyle modifications, individuals living with HIV-1 can lead a healthy, normal life.

In closing, the HIV-1 Drug Resistance - Genotypic test is an invaluable tool in managing HIV-1, contributing to personalized, effective treatment plans. With this test and the continued commitment to therapy and regular monitoring, individuals living with HIV-1 can continue to live fulfilling lives while suppressing their viral load.

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