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Lab Test

Histamine – Plasma

Histamine is an organic compound involved in local immune responses as well as regulating physiological function in the gut. It acts as a neurotransmitter, communicating important messages between different cells in your body. Histamine is most notably involved in allergic reactions and inflammation.


  • Profile Name: Histamine – Plasma
  • Sample Type: Blood
  • Preparations Required: No specific preparation or fasting is required for this test, but it's best to follow your healthcare provider's instructions.
  • Report Time: 8 days

The histamine plasma test measures the amount of histamine in your blood. This helps your healthcare provider determine if you're experiencing an allergic reaction or have a condition that causes excess histamine production. The test can also assist in diagnosing and monitoring certain types of mast cell disorders, where mast cells (a type of white blood cell) produce too much histamine.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

The histamine plasma test plays a crucial role in diagnosing conditions related to excessive histamine production, such as allergies, mastocytosis, or histamine intolerance. It aids in monitoring the effectiveness of treatment for these conditions.

No, fasting is not typically required for a histamine plasma test, but you should follow the instructions provided by your healthcare provider or laboratory.

No specific preparations are required for the histamine plasma test. However, you should inform your healthcare provider about any medications or supplements you're taking, as some could affect test results.

This test is generally ordered when a person exhibits symptoms suggestive of an allergy or mast cell disorder, such as flushing, itching, hives, abdominal cramps, or anaphylaxis (a severe allergic reaction).

The test measures the level of histamine in your blood. Abnormally high levels may indicate an allergic reaction, mast cell disorder, or a histamine-rich diet, among other conditions.

The frequency of the histamine plasma test depends on your specific medical situation and your doctor's recommendations. If you're undergoing treatment for a condition related to histamine levels, the test may be repeated to monitor the effectiveness of the treatment.

Histamine levels can vary widely among individuals, but a typical reference range is less than 0.3 nanograms per milliliter (ng/mL) of plasma. However, levels can vary depending on the specific testing laboratory.

Before the test, ensure you inform your healthcare provider about any medications or supplements you're taking. After the test, no special precautions are typically needed unless your healthcare provider advises otherwise.

Histamine levels can be affected by various factors, including food and drink (some foods are high in histamine), alcohol, certain medications, and physical or emotional stress. Some medical conditions, such as allergies and mast cell disorders, can also cause increased histamine levels.

If your histamine plasma test results are abnormal, you should consult with a specialist such as an allergist or immunologist, who can provide expert care and treatment advice based on these results.

The histamine plasma test involves a routine blood draw, which carries minimal risks, such as slight pain or bruising at the puncture site.

The histamine plasma test can help identify an ongoing allergic reaction, as histamine levels typically rise during such a reaction. However, it's not used to identify the specific allergen causing the reaction.

High histamine levels may indicate an allergic reaction, mast cell disorder, or histamine intolerance. However, your healthcare provider will interpret your results in the context of your symptoms and other medical information.

A healthcare professional will collect a blood sample from a vein in your arm using a needle. This sample is then processed to separate the plasma from the other components of the blood.

Yes, certain medications can affect histamine plasma test results. These include antihistamines, certain antidepressants, and some medications for acid reflux or peptic ulcer disease. You should always inform your healthcare provider about any medications you're taking.

In the vast landscape of health diagnostics, the histamine plasma test stands as a crucial tool in identifying and managing conditions linked to the immune system and inflammation. Even though it's a highly specialized test, it involves a simple and straightforward blood draw. As with any medical procedure, understanding the test and knowing what to expect can make the process easier. Armed with the knowledge about the role of histamine in your body and the significance of this test, you can be a more active participant in your healthcare journey. This proactive approach can go a long way in helping you achieve and maintain optimal health.

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