Book Heterophile Antibodies Monotest/ Paul Bunnel Test

Patient Preparing : No special preparation is needed for this test. You can continue your regular diet and activities.

₹ 1100


Infectious mononucleosis, also known as "mono" or the "kissing disease," is a common condition caused by the Epstein-Barr virus (EBV). It's most often seen in teenagers and young adults, but it can occur at any age. Symptoms can include fatigue, sore throat, fever, and swollen lymph nodes, especially in the neck.

The Heterophile Antibodies (HA) test, also known as the Monotest or the Paul-Bunnell test, is one of the diagnostic tests used to confirm a suspected infectious mononucleosis infection. This test detects the presence of heterophile antibodies, which are a type of antibody produced by the immune system in response to the EBV infection. These antibodies react with antigens (substances that stimulate an immune response) from other species, hence the name "heterophile."

Test Name Heterophile Antibodies (HA) (Infectious Mononucleosis) - Monotest/ Paul Bunnel Test
Sample Type Blood
Preparations Required No special preparation is needed for this test. You can continue your regular diet and activities.
Report Time 6 hours
Price in Hyderabad ₹ 1100

What are heterophile antibodies?

Heterophile antibodies are a type of antibody that reacts not only to the inducing antigen but also to unrelated antigens. They are typically formed in response to an infection with the Epstein-Barr virus, which causes infectious mononucleosis.

Why is the test performed?

The heterophile antibody test is performed to help diagnose infectious mononucleosis. If you have symptoms such as fever, sore throat, and swollen lymph glands, your healthcare provider may order this test to confirm a diagnosis of mono.

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How is the test performed?

The test requires a simple blood draw. The blood sample is then sent to a laboratory, where it is tested for the presence of heterophile antibodies.

How is the sample collected?

A healthcare provider will clean a site on your arm and insert a needle into a vein to collect a blood sample.

Do I need to fast before the test?

No, you don't need to fast before this test. You can eat and drink normally.

What do the test results mean?

A positive test result means that heterophile antibodies are present in your blood, indicating an infection with Epstein-Barr virus. A negative test result means that these antibodies are not present in your blood. However, it may also mean that it's too early in the infection for the antibodies to be detected.

How long does it take to get the results?

It typically takes 1 to 3 days to get the results of a heterophile antibody test.

Can this test be done at home?

No, this test requires a blood draw, which must be done by a healthcare provider.

Are there any risks associated with this test?

The risks associated with this test are minimal and are the same as for any routine blood draw. These may include slight pain or bruising at the site of the needle insertion.

Are there any medications or conditions that can affect the results of the test?

Certain medications can affect the results of the test, so it's important to inform your healthcare provider of any medications you're taking. Other viral infections can sometimes produce a positive result, leading to a false positive.

What is the treatment for infectious mononucleosis?

There is no specific treatment for infectious mononucleosis. Most treatment strategies focus on relieving symptoms such as fever and sore throat.

Can infectious mononucleosis be prevented?

As mononucleosis is caused by a virus, it can be difficult to prevent. However, avoiding close contact with someone who has mono, including sharing drinks or kissing, can reduce your risk.

What other tests might be performed to diagnose mono?

Other tests for mononucleosis may include a complete blood count (CBC) or tests for specific EBV antibodies.

What are some complications of infectious mononucleosis?

While mono typically resolves on its own, complications can occur. These may include an enlarged spleen, liver inflammation, and rarely, neurological complications such as encephalitis.

Which doctor should I consult if I have abnormal results?

If you have abnormal results, you should consult with your primary care physician or an infectious disease specialist.

How often should this test be done?

The heterophile antibody test is typically performed when a doctor suspects infectious mononucleosis based on a patient's symptoms and physical examination. There is no need for regular testing unless the symptoms persist or if complications are suspected.

Can I have infectious mononucleosis more than once?

It's unlikely. Once you've had mono, your body develops antibodies that protect you from getting infected with the virus again. However, the virus remains dormant in your body and can reactivate, although this rarely results in symptoms.

Can mono affect my liver?

Yes, mononucleosis can affect the liver, causing hepatitis (inflammation of the liver) or jaundice (yellowing of the skin and eyes). If you have mono and notice that your skin or eyes have turned yellow, seek medical attention right away.

What are some modifiable factors affecting the levels of heterophile antibodies?

There are no specific modifiable factors affecting the levels of heterophile antibodies. The level of these antibodies in the body is primarily determined by the immune response to an Epstein-Barr virus infection.

What are some non-modifiable factors affecting the levels of heterophile antibodies?

The primary non-modifiable factor affecting the levels of heterophile antibodies is the presence of an Epstein-Barr virus infection. Other factors include age and genetic predisposition.

Are there any side effects to the test?

The side effects of the heterophile antibodies test are similar to those of any other blood test. These might include slight pain or bleeding at the injection site, fainting, or feeling lightheaded.

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