Hepatitis B Virus Basal Core Promoter Mutation Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No specific preparation is needed for this test. However, it is recommended to inform your doctor of any medications or supplements you are taking.

₹ 5000


Hepatitis B Virus (HBV) is a viral infection that attacks the liver and can cause both acute and chronic disease. It is transmitted through contact with the blood or other body fluids of an infected person. In chronic HBV infections, the virus continues to replicate in the liver, which can eventually lead to serious diseases such as cirrhosis or liver cancer. The Basal Core Promoter (BCP) is a region in the HBV genome that is essential for the virus to replicate. Mutations in the BCP area can increase the activity of the virus and are associated with more severe liver disease and a higher risk of developing liver cancer.

The HBV Basal Core Promoter Mutation test is used to detect mutations in the basal core promoter region of the HBV genome. This information can help in assessing the risk of progression to more severe liver disease and may influence the management and treatment decisions for chronic HBV infection.

Test Name Hepatitis B Virus (HBV) Basal Core Promoter Mutation
Sample Type Blood
Preparations Required No specific preparation is needed for this test. However, it is recommended to inform your doctor of any medications or supplements you are taking.
Report Time 8 Days
Price in Hyderabad ₹ 5000

What is the Hepatitis B Virus Basal Core Promoter Mutation test?

This test analyzes the genetic material of the hepatitis B virus to detect mutations in the basal core promoter region, which is a part of the HBV genome that controls viral replication.

Why is the HBV Basal Core Promoter Mutation test important?

This test is crucial as mutations in the BCP region are associated with increased viral replication, more severe liver disease, and a higher risk of liver cancer. Understanding these mutations can influence treatment decisions and management of chronic HBV infection.

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Who should have this test?

Individuals with chronic HBV infection, especially those who have an increased risk of liver disease progression or are being evaluated for antiviral therapy, should consider this test.

How is the test performed?

A blood sample is taken from a vein in your arm. The sample is then sent to a laboratory, where the genetic material of the virus is analyzed for mutations in the BCP region.

What do the results mean?

If mutations in the BCP region are detected, it indicates that there is an increased risk of severe liver disease and liver cancer. This information can be used by your doctor to make informed decisions regarding your treatment and monitoring.

Can BCP mutations be treated?

While the mutations themselves cannot be reversed, antiviral medications can help to manage the replication of the virus. The treatment strategy may be modified based on the presence of BCP mutations.

What is the basal core promoter region?

The basal core promoter is a region in the HBV genome that is responsible for controlling the replication of the virus. Mutations in this area can increase the virus's ability to replicate, which can contribute to liver damage.

Is there any specific preparation required for the test?

No specific preparation is required for this test. However, it is essential to inform your doctor about any medications or supplements you are taking.

How can I reduce the risk of liver damage due to HBV infection?

To reduce the risk of liver damage, it is essential to follow your doctor’s recommendations regarding antiviral therapy, regular monitoring, and lifestyle changes such as avoiding alcohol and maintaining a healthy diet.

Can HBV infection be prevented?

Yes, HBV infection can be prevented through vaccination. It is also important to practice safe behaviors, such as using condoms and not sharing needles.

How often should I get tested for HBV and its mutations?

The frequency of testing depends on various factors including your viral load, liver function, and treatment. Your doctor will guide you regarding the appropriate frequency of testing.

What factors can affect the results of this test?

Certain medications and supplements can affect the results of this test. It is important to inform your doctor about any medications or supplements you are taking.

Which doctor should I consult if my test results indicate BCP mutations?

If the test results indicate BCP mutations, you should consult a hepatologist or an infectious disease specialist for further management and treatment.

Can BCP mutations be transmitted to others?

Yes, if you have chronic HBV infection with BCP mutations, it can be transmitted to others through blood or other body fluids.

Is it possible for BCP mutations to develop during antiviral therapy?

Yes, BCP mutations can develop during therapy. This is known as resistance, and it's one of the reasons why monitoring is important during treatment.

Detecting and understanding the significance of BCP mutations in HBV can be pivotal in the management of chronic hepatitis B infection. It helps in assessing the severity and progression of liver disease. Regular monitoring and adherence to the treatment regimen are critical for managing the condition effectively. It is important to maintain open communication with your doctor and follow the prescribed treatment and lifestyle recommendations. Through vigilant management, it is possible to limit the progression of HBV infection and maintain liver health.

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