HBV Drug Resistance Genotyping YMDD Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No specific preparation or fasting is required for this test

₹ 7500


Hepatitis B virus (HBV) is a major global health concern, causing acute and chronic liver disease. Antiviral medications have been developed to combat HBV, but drug resistance remains a significant challenge, particularly to the drug lamivudine, which targets the YMDD motif of the viral polymerase.

The HBV Drug Resistance Genotyping – YMDD test detects mutations in the YMDD region of the hepatitis B virus, indicating resistance to certain antiviral drugs. This information is vital for clinicians in choosing the most effective treatment plan for patients with HBV.

Test Name HBV Drug Resistance Genotyping – YMDD
Sample Type Blood
Preparations Required No specific preparation or fasting is required for this test
Report Time 3 Days
Price in Hyderabad ₹ 7500

Why is the HBV Drug Resistance Genotyping – YMDD test important?

The test is crucial for detecting mutations in the HBV genome that result in resistance to antiviral drugs. By identifying these mutations, physicians can select the most effective treatment options for individual patients.

Is fasting required for this test?

No, fasting is not required for the HBV Drug Resistance Genotyping – YMDD test.

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Is any specific preparation required for this test?

There is no specific preparation necessary for this test.

When should this test be done?

The test should be performed when a patient with HBV shows signs of treatment failure, such as an increase in viral load or liver enzymes despite being on antiviral therapy.

What information does the HBV Drug Resistance Genotyping – YMDD test provide?

The test identifies mutations in the YMDD motif of the HBV polymerase, which can confer resistance to certain antiviral drugs. This information can help guide changes in treatment strategy.

How often should this test be performed?

The frequency of the test depends on your doctor's advice and is generally performed when a patient's response to antiviral therapy is suboptimal.

What are the normal values for this test?

In this type of genetic test, normal values would indicate no mutations detected in the YMDD motif. However, the presence of certain mutations would suggest drug resistance.

Are there any precautions to be taken for the test?

No specific precautions are needed for the test. But it's essential to inform your doctor about any medications you're currently taking.

What factors can affect the test results?

Factors that may affect the results include recent changes in medication or the stage of HBV infection.

What are the modifiable and non-modifiable factors affecting HBV drug resistance?

Modifiable factors may include adherence to medication, while non-modifiable factors could be the stage of the disease or the presence of certain mutations in the virus.

Which doctor should be consulted in case of an abnormal test result?

In case of an abnormal result, a hepatologist or an infectious disease specialist should be consulted.

What does it mean if I have a mutation in the YMDD motif?

A mutation in the YMDD motif suggests that the HBV is resistant to certain antiviral drugs, and alternative treatment options may need to be considered.

Can drug resistance be reversed?

Once a drug-resistant mutation occurs, it can't usually be reversed. However, alternative treatment options are available that can effectively control the virus.

Can HBV drug resistance be prevented?

Adherence to the prescribed medication regimen is crucial in preventing drug resistance. In some cases, combination therapy might be recommended to reduce the risk of developing drug-resistant HBV.

Is there a cure for hepatitis B?

While there is no definitive cure for hepatitis B, the disease can be managed effectively with antiviral therapy, regular monitoring, and supportive care.

The HBV Drug Resistance Genotyping – YMDD test offers valuable insights into the genetic makeup of the hepatitis B virus within an individual patient, aiding clinicians in tailoring treatment strategies that can effectively control the virus. Timely and accurate detection of drug resistance is vital in managing chronic HBV infection, and contributes to improving patient outcomes. As always, regular consultations and follow-ups with your doctor are essential when managing any health concerns

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