Lab Test

GST Mutation (Glutathione-S-Transferase)

The Glutathione S-transferases (GSTs) are a family of enzymes that play a crucial role in the detoxification of harmful compounds in the body. These enzymes function by conjugating the small molecule glutathione to toxic compounds, making them more soluble and easier for the body to excrete. Several different types of GST enzymes exist, and genetic mutations in the genes that encode these enzymes can have significant effects on an individual's ability to detoxify certain harmful substances.

  • Profile Name: GST Mutation (Glutathione-S-Transferase)
  • Sample Type: Blood Sample
  • Preparations Required: No specific preparation is required before this test. Just continue your normal diet and activities unless your doctor instructs otherwise.
  • Report Time: 5 weeks

GST mutations have been associated with an increased risk of several types of cancer, including lung, bladder, and colon cancer. This is thought to occur because individuals with these mutations are less able to detoxify and excrete certain carcinogens, allowing these harmful substances to accumulate and cause damage to cells.

Testing for GST mutations can provide important information for risk assessment and personalized treatment strategies in a variety of clinical settings. For instance, individuals found to have a GST mutation might be advised to avoid certain environmental carcinogens, such as cigarette smoke, or might be more closely monitored for the early detection of certain types of cancer.

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Reporting of the sample at lab
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Frequently Asked Questions

A GST mutation test is a genetic test that identifies changes in the genes that encode the glutathione S-transferase enzymes.

Individuals who have a family history of certain types of cancer, such as lung, bladder, or colon cancer, might consider this test. It can also be helpful for those with exposure to environmental carcinogens.

A GST mutation test involves drawing a blood sample that is then sent to a lab for analysis.

Having a GST mutation means that your body might be less able to detoxify certain harmful substances. This can increase your risk for certain types of cancer.

A blood sample is used for this test.

No specific preparation is required before this test.

The risks associated with this test are minimal and similar to those of a regular blood draw.

While lifestyle factors can influence the level of certain toxins in your body, they will not affect the results of the GST mutation test, which looks for genetic changes.

Modifiable factors include exposure to environmental toxins, diet, smoking, alcohol consumption, and physical activity levels.

Non-modifiable factors include age, gender, family history of cancer, and having a GST mutation.

If you test positive for a GST mutation, it's essential to discuss the results with your doctor to understand what they mean for your health. You might be advised to take certain precautions, like avoiding exposure to specific toxins and being regularly screened for cancer.

If you test positive for a GST mutation, you should discuss the results with a genetic counselor or a doctor specializing in medical genetics.

Fasting is not typically required for a GST mutation test.

The frequency of testing depends on individual circumstances and is typically determined by your doctor.

The GST Mutation Test is a vital tool in understanding your body's ability to detoxify certain harmful substances. It can provide valuable information about your risk of developing certain types of cancer, especially if you have a family history or are exposed to certain environmental toxins. As with any health concern, early detection and management are key, and regular consultations with your doctor can ensure that you are taking the necessary steps to maintain your health. Knowledge is power, and understanding your genetic makeup can empower you to make informed decisions about your health and well-being.

GST Mutation (Glutathione-S-Transferase)
₹ 20000
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