Glycine - Quantitative CSF Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No specific preparation is needed for this test.

₹ 7500


The Glycine - Quantitative CSF Test is a specialized laboratory test that measures the level of glycine in the cerebrospinal fluid (CSF). Glycine is an amino acid, a building block of proteins, which also plays a role as a neurotransmitter in the central nervous system. It's known to have an inhibitory effect, calming the activity of the brain cells and the central nervous system. This test is often used in the diagnosis of certain metabolic disorders that affect glycine metabolism, such as nonketotic hyperglycinemia (NKH).

The test involves taking a sample of the cerebrospinal fluid, which is the fluid surrounding the brain and spinal cord. This fluid provides a cushion for the brain and spinal cord, and it also carries nutrients and removes waste from the brain. The levels of certain substances, including glycine, in the CSF can provide valuable information about a person's health.

Test Name Glycine - Quantitative CSF Test
Sample Type CSF (Cerebrospinal Fluid)
Preparations Required No specific preparation is needed for this test.
Report Time 4 days
Price in Hyderabad ₹ 7500

Why is the Glycine - Quantitative CSF Test important?

This test is important in diagnosing and monitoring certain metabolic disorders, such as nonketotic hyperglycinemia (NKH), a rare genetic disorder that affects glycine metabolism. High levels of glycine in the CSF can cause seizures, breathing and feeding difficulties, and developmental delay.

Do I need to fast for this test?

No, fasting is not required for this test.

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When should I get this test done?

Your doctor may order this test if you're showing symptoms suggestive of a disorder that affects glycine metabolism, such as seizures, breathing or feeding difficulties, and developmental delay, especially in infants.

What does this test measure?

This test measures the level of glycine in the cerebrospinal fluid. Elevated levels of glycine in the CSF can be indicative of disorders affecting glycine metabolism.

How often should I get tested?

The frequency of this test will depend on your doctor's recommendations, based on your symptoms and health condition.

What are the normal values for this test?

Normal values for glycine in the CSF can vary between laboratories. Your lab report should contain the specific reference range for your test.

What precautions should I take before this test?

There are no special precautions needed for this test. However, always inform your doctor about any medications, supplements, or treatments you're undergoing as they may affect your results.

What factors can affect the glycine levels in my CSF?

Factors that can affect glycine levels in your CSF include your diet, certain medications, and genetic or metabolic disorders that affect glycine metabolism.

If the test results are abnormal, which doctor should I consult?

If your test results are abnormal, you should consult with your primary care doctor, who may refer you to a neurologist or a metabolic specialist for further investigation.

What does a high glycine level in my CSF indicate?

A high level of glycine in the CSF could suggest a disorder of glycine metabolism, such as nonketotic hyperglycinemia. These disorders often lead to an excess of glycine in the body, which can cause a range of symptoms, from mild to severe.

What does a low glycine level in my CSF indicate?

Low levels of glycine in the CSF are typically normal. However, very low levels could be a sign of malnutrition or other metabolic problems, although this is rare.

What are the symptoms of disorders that affect glycine metabolism?

Symptoms of disorders that affect glycine metabolism can include seizures, breathing and feeding difficulties, developmental delay, and lethargy.

Are there treatments available if my glycine levels are too high?

Treatment will depend on the cause of the elevated glycine levels. For genetic disorders like nonketotic hyperglycinemia, treatment may include dietary modifications, medications to control symptoms, and in some cases, organ transplantation.

Can medications influence my glycine levels?

Yes, certain medications can influence glycine levels in your body. Always inform your doctor about any medications or supplements you're taking.

Can a change in diet impact my glycine levels?

While your diet can impact glycine levels, it's important to note that dietary changes alone are unlikely to significantly alter your glycine levels if you have a genetic disorder that affects glycine metabolism. You should always consult your doctor or a nutritionist before making any major changes to your diet.

Understanding your glycine levels and how they interact with your overall health can be a crucial part of managing disorders that affect glycine metabolism. The Glycine - Quantitative CSF Test provides valuable data in this regard. If your glycine levels are high or if you're experiencing symptoms, it's important to have open communication with your doctor about your concerns, symptoms, and any lifestyle factors that could impact your health. With the right care and management, many people with disorders that affect glycine metabolism can lead fulfilling and healthy lives.

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