Glutamic Acid Decarboxylase 65 IgG Antibodies Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No specific preparation is necessary for this test, but it is recommended to inform the doctor of any medications or supplements taken.

₹ 6500


The Glutamic Acid Decarboxylase 65 (GAD-65) IgG Antibodies Test is a blood test that assesses the presence of antibodies against glutamic acid decarboxylase 65 (GAD-65), an enzyme found in the pancreas and central nervous system. GAD-65 is vital in the production of a neurotransmitter called gamma-aminobutyric acid (GABA) that regulates communication between nerve cells. The presence of antibodies against GAD-65 may indicate an autoimmune response, where the body’s immune system attacks its own tissues. This test is commonly used in the diagnosis and management of Type 1 Diabetes and some neurological disorders, such as Stiff Person Syndrome.

Test Name Glutamic Acid Decarboxylase 65 (GAD-65) IgG Antibodies Test
Sample Type Blood
Preparations Required No specific preparation is necessary for this test, but it is recommended to inform the doctor of any medications or supplements taken.
Report Time 24 hours
Price in Hyderabad ₹ 6500

Why is the GAD-65 IgG Antibodies Test performed?

This test is usually performed to help diagnose Type 1 Diabetes or to differentiate it from Type 2 Diabetes. It is also used to assess autoimmune neurological disorders, such as Stiff Person Syndrome, where antibodies against GAD-65 are present.

How is the GAD-65 IgG Antibodies Test performed?

A healthcare professional will draw a blood sample from a vein in your arm. The blood sample is then sent to a laboratory where it will be tested for the presence and levels of antibodies against GAD-65.

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What do the results of the test mean?

A positive test result means that antibodies against GAD-65 are present in the blood. This may indicate an autoimmune condition such as Type 1 Diabetes or Stiff Person Syndrome. A negative result means that antibodies are not present or are at levels too low to detect.

Are there any risks associated with this test?

The risks associated with the blood draw are minimal. Some individuals may experience pain, bruising, or bleeding at the puncture site. Infection is a rare complication.

Can the results of this test predict the development of Type 1 Diabetes?

Yes, the presence of GAD-65 antibodies can be an early marker for the risk of developing Type 1 Diabetes, especially in individuals with a family history or other autoantibodies.

What is the role of GAD-65 in the body?

GAD-65 is an enzyme involved in the synthesis of GABA, a neurotransmitter that plays a key role in regulating communication between nerve cells, and is essential for muscle coordination and controlling brain activity.

What is Stiff Person Syndrome?

Stiff Person Syndrome is a rare neurological disorder characterized by stiffness, muscle spasms, and functional impairment. It is often associated with the presence of GAD-65 antibodies, indicating an autoimmune component.

Can medication affect the results of this test?

Certain medications, especially those affecting the immune system, might impact the levels of GAD-65 antibodies. Inform your doctor of all medications you are taking.

Is this test used in monitoring the progression of Type 1 Diabetes?

This test is not typically used for monitoring the progression of Type 1 Diabetes but can be valuable in the initial diagnosis and understanding the autoimmune aspect of the condition.

Can lifestyle or dietary changes affect the levels of GAD-65 antibodies?

There is no concrete evidence that lifestyle or dietary changes can significantly affect the levels of GAD-65 antibodies, as their presence is primarily associated with autoimmune responses.

Can you have Type 1 Diabetes without GAD-65 antibodies?

Yes, not all individuals with Type 1 Diabetes have GAD-65 antibodies. There are also other autoantibodies associated with Type 1 Diabetes.

What are the treatment options for conditions associated with GAD-65 antibodies?

Treatment options depend on the underlying condition. For Type 1 Diabetes, insulin therapy is necessary. For Stiff Person Syndrome, treatment may include medications to control symptoms and improve mobility.

Are there other antibodies associated with Type 1 Diabetes?

Yes, besides GAD-65 antibodies, there are other antibodies associated with Type 1 Diabetes, such as insulin autoantibodies (IAA) and islet cell antibodies (ICA).

Is there a cure for conditions associated with GAD-65 antibodies?

There is no cure for Type 1 Diabetes or Stiff Person Syndrome. Treatment focuses on managing symptoms and preventing complications.

Which doctor should be consulted in case of a positive GAD-65 IgG Antibodies Test?

If the test comes back positive, consulting a general physician is advisable, who may then refer you to an endocrinologist or neurologist based on the underlying condition.

The Glutamic Acid Decarboxylase 65 (GAD-65) IgG Antibodies Test is a vital diagnostic tool for assessing autoimmune conditions such as Type 1 Diabetes and Stiff Person Syndrome. Understanding the results is key to managing the condition effectively. Consult your doctor for personalized medical advice and information regarding your health. This test plays an integral role in the timely diagnosis and management of conditions associated with GAD-65 antibodies.

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