CD123, or Interleukin-3 receptor alpha (IL-3Rα), is a protein expressed on the surface of many immune cells, including basophils, eosinophils, monocytes, dendritic cells, and a subtype of B lymphocytes. It plays a critical role in the growth and differentiation of hematopoietic (blood-forming) cells. Certain malignancies, particularly acute leukemia and blastic plasmacytoid dendritic cell neoplasm (BPDCN), show an abnormal increase in CD123 expression.
Flow cytometry is a laboratory method that is used to measure physical and chemical characteristics of cells and particles. In Flowcytometry - CD123, this technology is utilized to examine the presence and amount of CD123 protein on cells, aiding in the identification of particular cell types and conditions.
This test plays an instrumental role in diagnostics, especially for hematological disorders, as it assists in identifying abnormal immune cells that might be present in certain types of leukemia and lymphomas. By providing a quantified measurement of CD123 expression on cells, this test helps clinicians tailor suitable treatment strategies for patients.
Test NameFlowcytometry - CD123
Sample TypeBlood or Bone Marrow
Preparations RequiredNo specific instructions or preparations are required for this test
Report Time2 days
Why is the Flowcytometry - CD123 test important?
The Flowcytometry - CD123 test is crucial as it helps identify and quantify CD123 protein expression on immune cells. Abnormally high levels of CD123 can indicate certain types of malignancies, aiding in diagnosis and treatment planning.
Do I need to fast for the Flowcytometry - CD123 test?
No, fasting is not required for this test.
Home Sample Collection Process
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Book your convenient slot
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Sample Collection by Phlebotomist
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Reporting of the sample at lab
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Frequently Asked Questions
Your doctor may recommend this test if they suspect a hematological disorder, especially leukemia or lymphoma. It is also commonly used in research studies.
This test measures the expression of CD123, a protein found on the surface of certain immune cells. High levels can suggest an abnormal proliferation of these cells, as seen in certain types of blood cancers.
The frequency of the test depends on your specific medical condition. Your doctor will guide you based on your health status and treatment plan.
Normal values may vary depending on the specific lab and method used for the test. Typically, a normal result is the absence of an abnormally high level of CD123-expressing cells.
You should consult your doctor or a hematologist (a specialist in blood disorders) if your test results are abnormal.
Yes, some medications may affect the test results. It is essential to inform your doctor about any medication you are currently taking.
The test involves a routine blood draw, which may cause minor discomfort at the injection site. Any discomfort is generally short-lived and manageable.
There are no specific post-test precautions. However, it's important to keep the injection site clean to prevent infection.
Yes, the test can aid in diagnosing certain types of blood cancers, like acute leukemia and blastic plasmacytoid dendritic cell neoplasm (BPDCN), which typically show a high level of CD123 expression.
Certain medications may affect CD123 levels. However, it's best to discuss this with your doctor.
Non-modifiable factors that can affect CD123 levels include genetic factors and certain diseases like leukemia and lymphoma.
High levels of CD123 may suggest the presence of certain blood cancers. Your doctor will interpret your test results in the context of your overall health and other test results.
No, this test requires specialized equipment and trained professionals to perform and interpret the results. Therefore, it needs to be done in a medical lab or a healthcare facility.
The Flowcytometry - CD123 test is a significant diagnostic tool in the field of hematology and oncology. It helps in identifying abnormalities in immune cells and can point to certain types of blood cancers. As with all medical tests, it's essential to discuss the results with your doctor to understand what they mean for your health. Regular monitoring and follow-ups are crucial, especially if you are undergoing treatment for a hematological disorder.
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