The CD117 molecule, also known as c-Kit or Stem Cell Factor Receptor (SCFR), is a protein that is important in certain cellular processes, including cell differentiation, proliferation, and survival. The protein is encoded by the KIT gene. CD117 is a type of receptor tyrosine kinase, a class of proteins involved in transmitting chemical signals within cells.
Flow cytometry is a powerful tool that allows for the measurement of these and other cell properties. It is a technology that provides rapid multi-parametric analysis of single cells in a fluid stream. CD117 expression can be analyzed through the flow cytometry technique.
The use of CD117 expression in flow cytometry can help in the diagnosis and monitoring of certain conditions. CD117 is often overexpressed in several types of cancers, including gastrointestinal stromal tumors (GISTs), mastocytosis, and some forms of leukemia. Hence, CD117 can be used as a target for therapeutic intervention in these malignancies.
This test is performed when a doctor suspects these conditions and wants to confirm the diagnosis or monitor the effectiveness of treatment.
Test NameFlowcytometry - CD117
Sample TypeBlood or Bone Marrow
Preparations RequiredNo fasting is required for the test. Always follow the instructions provided by the doctor or lab technician.
Report Time2 days
What is the importance of getting this test done?
The Flowcytometry CD117 test helps in diagnosing and monitoring conditions like gastrointestinal stromal tumors (GISTs), mastocytosis, and certain types of leukemia. It is vital in the treatment process as it helps doctors to understand the disease better and to determine the most effective treatment plan.
Is fasting required for the Flowcytometry CD117 test?
No, fasting is not required for the Flowcytometry CD117 test. However, always follow your doctor’s instructions.
Home Sample Collection Process
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Book your convenient slot
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Sample Collection by Phlebotomist
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Reporting of the sample at lab
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Download Reports
Frequently Asked Questions
The frequency of the Flowcytometry CD117 test depends on the medical condition and the doctor's discretion. It may be performed periodically if you're undergoing treatment for conditions such as GISTs, mastocytosis, or leukemia to monitor the effectiveness of the treatment.
No special precautions are required before the Flowcytometry CD117 test.
The normal values for the Flowcytometry CD117 test can vary based on the specific lab's reference range and the patient's medical history. Generally, normal cells do not overexpress CD117. Any significant overexpression may indicate a pathological condition.
Although rare, false-positive results can occur due to technical errors or certain physiological conditions. Discuss any concerns with your doctor.
Modifiable factors may include certain medications or treatments that could affect the expression of CD117.
Non-modifiable factors include genetic mutations leading to the overexpression of CD117.
If your CD117 levels are abnormal, you should consult a hematologist or an oncologist.
There is no specific preparation needed for this test. However, always follow the advice given by your doctor or the testing laboratory.
Certain medications may affect the test results. It is essential to inform your doctor about all the medications you are taking.
The test provides information about the expression of CD117 in the cells. Overexpression of CD117 can indicate certain types of cancer and other conditions.
The test is generally safe. Risks are associated with the blood draw and may include slight pain or bruising at the injection site.
No, the Flowcytometry CD117 test requires a specialized lab setup and cannot be performed at home.
Overexpression of CD117 is often associated with certain types of cancers and other conditions.
The Flowcytometry CD117 test is a significant step in diagnosing and monitoring diseases related to the overexpression of CD117. It aids the doctor in determining the condition's severity and deciding the most effective treatment plan. As with any test, it is essential to discuss the results with your doctor, who can provide you with appropriate advice based on your overall health status and medical history.
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