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Lab Test

Flowcytometry - B-Cell Absolute Counts (CD19/CD20/CD45) Test

B-cells are a crucial component of our immune system, responsible for producing antibodies to ward off harmful foreign invaders. Tracking B-cell counts in the body can aid in diagnosing and monitoring various diseases, particularly those associated with the immune system and blood cancers. The Flowcytometry - B-Cell Absolute Counts (CD19/CD20/CD45) test is a specialized diagnostic method used for this purpose.

  • Profile Name: Flowcytometry - B-Cell Absolute Counts (CD19/CD20/CD45) Test
  • Sample Type: Blood
  • Preparations Required: No fasting is required before this test. There are no specific instructions for preparation or restrictions on water consumption. It's a routine blood test, and you can eat and drink normally before the test.
  • Report Time: 2 days

Flow cytometry leverages the principles of light to gather multifaceted data from particles and cells. The B-Cell Absolute Counts test specifically looks at markers, or proteins, known as CD19, CD20, and CD45. These proteins exist on the surface of B cells and are a key in identifying and studying these cells. Variations in the normal count of these markers can indicate an underlying health condition.

Home Sample Collection Process

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Book your convenient slot
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
Reporting of the sample at lab
Reporting of the sample at lab
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Download Reports
Frequently Asked Questions

This test plays a crucial role in diagnosing, monitoring, and determining treatment strategies for diseases associated with the immune system and specific types of blood cancers. For example, low B-cell counts could indicate conditions like HIV, leukemia, lupus, while high B-cell counts might suggest lymphomas or multiple myeloma.

No, fasting is not required for this test. You can continue with your usual diet and water consumption.

Your doctor might order this test if you present with symptoms suggesting a possible immune system disorder or blood cancer, or if you're undergoing treatment for these conditions to monitor the progress and effectiveness of the therapy.

This test provides information on the number of B cells in the blood sample and the proportion of these cells expressing the CD19, CD20, and CD45 markers. This data can indicate the presence, progression, or regression of diseases associated with these cells.

The frequency of this test depends on the individual's health condition and the doctor's assessment. In some cases, it might be a one-time test, or it might be repeated at intervals to monitor the condition or the effectiveness of a treatment.

Normal values can vary depending on the laboratory conducting the test, but generally, B cells should constitute about 5-15% of the total lymphocyte population. It's best to discuss the results with your doctor, who can interpret them in the context of your overall health and medical history.

As this test is a standard blood test, no special precautions are necessary. If you're on any medication that might affect the results, discuss this with your doctor.

Various factors can influence the levels of these markers, including active infection, immunodeficiency diseases, autoimmune diseases, and malignancies such as leukemia and lymphomas.

If your test results are abnormal, you should consult with a hematologist or an immunologist who can interpret your results and guide you on the next steps.

Yes, certain medications, especially those that suppress the immune system, can affect your B-cell count. It's important to inform your doctor of any medication you're currently taking.

These are different proteins present on the surface of B cells at different stages of their development. CD19 and CD20 are commonly used to identify mature B cells, while CD45 is found on all nucleated hematopoietic cells and has different isoforms expressed on B cells at different stages.

Yes, it is safe to take this test during pregnancy. If you're pregnant and your doctor has recommended this test, it's crucial to follow through as it can help detect conditions that might affect your health or the health of your baby.

The test involves a standard blood draw, which might cause a little discomfort or a slight prick at the injection site. But generally, it's not considered painful.

While this test can give valuable information about the immune system and can help diagnose certain types of blood cancers, it does not cover all types. There are many different types of blood cancers, each requiring different diagnostic tests.

The test is safe and carries minimal risk, similar to a regular blood draw. You may experience a slight bruise or swelling at the needle site, but this usually resolves on its own within a few days.

The Flowcytometry - B-Cell Absolute Counts (CD19/CD20/CD45) test is a significant part of diagnosing and monitoring various diseases, particularly those involving the immune system and blood cancers. Although the technology behind this test may seem complex, the insights it offers into immune health are invaluable. If your doctor has recommended this test, rest assured it is a routine procedure that can provide crucial information about your health.

Flowcytometry - B-Cell Absolute Counts (CD19/CD20/CD45)
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