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Lab Test

TdT in Flow Cytometry

TdT in Flow Cytometry

The powerful lens of flow cytometry unveils the universe within a single drop of blood or bone marrow. By tagging cellular components with fluorescent markers, we can measure properties like size, shape, and more interestingly, the presence of certain proteins. One of these proteins that we can detect is Terminal Deoxynucleotidyl Transferase (TdT), an enzyme which has significant diagnostic value in certain blood disorders.


  • Test NameTdT in Flow Cytometry
  • Sample TypeBlood or Bone Marrow
  • Preparations RequiredNo specific preparations such as fasting or water restriction are required. Please do inform your doctor about any medications or dietary supplements you're taking prior to the test.
  • Report Time2 days

TdT, predominantly found in immature, developing lymphoid cells, becomes an indicator of certain leukemias when detected in abnormal quantities or in unexpected cell populations. Detecting and quantifying TdT through flow cytometry has thus become a critical part of diagnosing and monitoring these conditions. It also offers valuable insights into the nature of the disease, aiding in therapy decisions and prognosis evaluation.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

TdT plays a significant role in diagnosing and monitoring certain types of leukemia, including Acute Lymphoblastic Leukemia (ALL) and some forms of Acute Myeloid Leukemia (AML). The presence or absence of TdT can also assist in distinguishing between different subtypes of leukemia.

No, fasting is not necessary before this test. It's always a good idea to follow your doctor's specific instructions before any medical test.

This test measures the presence and quantity of TdT, an enzyme found in immature lymphoid cells. Anomalies in TdT levels can indicate certain types of leukemia.

The frequency of the test depends on the specific medical condition and the doctor's recommendations. It's typically performed when leukemia is suspected or for monitoring response to treatment in diagnosed cases.

In healthy individuals, TdT is not typically found in circulating blood cells. However, its presence doesn't necessarily mean disease. Your doctor will interpret your results in the context of your overall health and specific circumstances.

No specific precautions are required for the TdT test. As always, it's important to inform your doctor about any medications or supplements you're currently taking, as they might influence the test results.

The results can be influenced by a variety of factors, including certain medications, immune system disorders, or other conditions affecting blood cells. Some factors are modifiable, like lifestyle habits, while others, such as genetics, are not.

If your results are abnormal, you should consult with a hematologist, a doctor specializing in blood disorders. They will provide further guidance and potential treatment options based on your specific situation.

The test involves a blood or bone marrow draw, which carries minor risks such as bruising or infection at the needle site. Serious complications are rare.

An abnormal result may indicate leukemia, but it is not conclusive. Further tests may be required to confirm the diagnosis.

Yes, certain medications can affect the results of the TdT test. Always inform your doctor about any medications or supplements you are taking.

While you cannot prevent certain conditions like leukemia, maintaining a healthy lifestyle can support your overall health and immune function, possibly influencing the course of certain diseases.

Treatment options depend on the specific condition diagnosed. For leukemia, treatments can include chemotherapy, targeted therapy, immunotherapy, or stem cell transplantation.

Some genetic conditions associated with leukemia can be detected before birth. However, many conditions affecting the TdT test results develop later in life or are due to environmental factors.

The impact on lifespan depends on the specific condition and its severity. Early detection and treatment often improve prognosis and can potentially extend lifespan.

Navigating the landscape of health can be daunting, but tools like the TdT in flow cytometry provide a roadmap to understanding what's happening at the cellular level. Armed with the knowledge it provides, doctors and patients can together make informed decisions and take the necessary steps towards achieving optimal health. After all, understanding is the first step in any journey, including the journey to health.

Flowcytometry - TdT
₹ 1500
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