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FISH for PDGFR – B (Platelet Derived Growth Factor Receptor – beta)

FISH for PDGFR – B (Platelet Derived Growth Factor Receptor – beta)

Fluorescence In Situ Hybridization (FISH) for PDGFR-B is a diagnostic test that looks for genetic abnormalities involving the Platelet-Derived Growth Factor Receptor Beta (PDGFR-B) gene. PDGFR-B is a gene that encodes for a cell surface receptor, which plays a crucial role in cell signaling pathways that regulate cell growth, division, and development. In particular, this receptor is important for the development of blood vessels and the migration of cells within the body. However, when abnormalities occur, such as rearrangements involving the PDGFR-B gene, it can lead to various diseases including certain types of leukemia and other disorders.

Understanding the genetic profile of an individual can provide important information for the diagnosis, prognosis, and treatment planning of diseases. The FISH for PDGFR-B test specifically looks for rearrangements of the PDGFR-B gene which may be associated with various hematological disorders.

  • Test NameFISH for PDGFR – B (Platelet Derived Growth Factor Receptor – beta)
  • Sample TypeBlood or Bone Marrow
  • Preparations RequiredNo specific preparation is required.
  • Report Time5 days

Home Sample Collection Process

Book your convenient slot
Book your convenient slot
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
Reporting of the sample at lab
Reporting of the sample at lab
Download Reports
Download Reports
Frequently Asked Questions

A sample of blood or bone marrow is taken from the patient. The sample is then processed in a laboratory where special probes are used to visualize the PDGFR-B gene under a microscope.

No special preparation is needed for the FISH for PDGFR-B test.

A negative result suggests that there is no detectable rearrangement involving the PDGFR-B gene in the analyzed cells.

The test itself has very few risks and is similar to having blood drawn for routine testing. However, bone marrow biopsy, if required, can cause discomfort and has slightly more risks.

Lifestyle choices such as diet, exercise, and exposure to environmental toxins can potentially affect the expression of PDGFR-B. Medication can also modify its activity.

The frequency of testing varies depending on the underlying condition and the doctor’s recommendation.

If you have abnormal results, you should consult a hematologist or oncologist as they specialize in blood disorders and cancers.

Yes, FISH for PDGFR-B is also used in research settings to understand the role of PDGFR-B in different diseases and to develop new therapies.

It's important to remember that while genetic testing can provide valuable information, the interpretation and management of test results should be performed by a healthcare professional. Understanding the genetic aspects of blood disorders can be an essential component of personalized medicine and tailored treatment strategies. However, it is just one part of a comprehensive approach to managing these complex conditions. Discuss the results and the best course of action with your doctor to make well-informed healthcare decisions.

FISH for PDGFR ? B (Platelet Derived Growth Factor Receptor ? beta)
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Locations Near You in Hyderabad
  • 4KM from Madhapur
  • 3KM from Banjara Hills
  • 1.9KM from Yusufguda
  • 3KM from Madhura Nagar
  • 5KM from Shaikpet