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FISH for del(7q)

FISH for del(7q)

Fluorescence In Situ Hybridization, commonly known as FISH, for del(7q) is a specialized test used to detect the deletion of a part of the long arm of chromosome 7. This deletion is often linked to certain hematological disorders, such as Myelodysplastic Syndromes (MDS) and acute myeloid leukemia (AML). The test plays a crucial role in the diagnosis, risk stratification, and management of patients with these blood disorders.

Chromosome 7 abnormalities, including the deletion of the long arm (7q), have been identified as common chromosomal abnormalities in various hematological disorders. FISH for del(7q) uses fluorescent probes that bind to specific regions of chromosome 7. The probes are viewed under a fluorescence microscope to check for the presence of a deletion in the long arm of chromosome 7.


  • Test NameFISH for del(7q)
  • Sample TypeBlood or Bone Marrow
  • Preparations RequiredNo special preparation is needed for this test. However, it is always recommended to follow any instructions provided by your doctor.
  • Report Time5 days

What is the FISH for del(7q) test used for?

FISH for del(7q) is used to detect deletions in the long arm of chromosome 7, which can be associated with hematological disorders such as Myelodysplastic Syndromes (MDS) and acute myeloid leukemia (AML). It is essential for diagnosis and planning appropriate treatment.

How is the test performed?

The test is performed on a sample of blood or bone marrow. The sample is treated with fluorescent probes specific for chromosome 7. Under a special microscope, a technician can determine if there is a deletion in the long arm of chromosome 7.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

If the test detects a deletion in the long arm of chromosome 7, it suggests the presence of a chromosomal abnormality that is associated with certain hematological disorders. Your doctor will use this information to make a diagnosis and plan treatment.

The presence of a 7q deletion may influence the choice of therapy, including the possibility of using specific targeted therapies. It is also used to assess prognosis and may indicate a need for more aggressive treatment strategies.

The risks are minimal and are primarily related to the blood draw. In cases where a bone marrow sample is needed, there might be some pain, bleeding, or risk of infection at the biopsy site.

No fasting or special preparation is needed for this test. It’s important to follow any specific instructions that your doctor might give you.

This test is typically recommended for individuals who have signs or symptoms suggestive of a hematological disorder, or abnormal findings on complete blood counts or other blood tests.

Additional tests such as complete blood counts, bone marrow biopsy, and other cytogenetic tests might be performed to evaluate the health of your blood and bone marrow.

Deletion of 7q in hematological disorders is usually acquired and not inherited. However, it’s important to discuss your family history and any genetic concerns with your doctor.

The deletion of 7q can be associated with different types of blood disorders. These disorders can affect your blood cells’ ability to function properly, which might cause anemia, increased risk of infections, and other symptoms.

This specific FISH test is designed to detect the deletion of the long arm of chromosome 7. However, there are various FISH tests available that can detect different chromosomal abnormalities.

If the test results are abnormal, it is advisable to consult a hematologist for further evaluation and management.

Treatment depends on the specific disorder and the individual's health status. Common treatments for hematological disorders associated with del(7q) include chemotherapy, blood transfusions, and in some cases, stem cell transplantation.

Management of the condition involves regular monitoring and following the treatment plan outlined by your doctor. It's also important to maintain a healthy lifestyle and keep communication open with your healthcare team.

The prognosis varies based on the specific disorder, the extent of the chromosomal abnormality, and the individual’s overall health. Your doctor can provide more detailed information based on your condition.

FISH for del(7q) is an essential test in the diagnosis and management of various hematological disorders. Understanding the significance of this chromosomal abnormality and its impact on your health is crucial. Regular monitoring and following a treatment plan prescribed by your doctor can help manage the condition effectively.

FISH for del7q
₹ 3900
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  • 4KM from Madhapur
  • 3KM from Banjara Hills
  • 1.9KM from Yusufguda
  • 3KM from Madhura Nagar
  • 5KM from Shaikpet