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FISH for CSF1R Gene Rearrangement

FISH for CSF1R Gene Rearrangement

Fluorescence In Situ Hybridization, commonly known as FISH, for CSF1R Gene Rearrangement is a diagnostic test that is utilized to identify abnormalities in the CSF1R gene. The CSF1R gene encodes for the colony-stimulating factor 1 receptor, which is a type of protein found on the surface of certain cells, including some white blood cells. This receptor is essential in regulating the production and development of specific types of white blood cells called macrophages.

Abnormalities in the CSF1R gene, particularly gene rearrangements, can be associated with various medical conditions including hematologic disorders and certain types of cancer, such as tenosynovial giant cell tumors. In some cases, CSF1R gene abnormalities may be a target for specific therapeutic interventions.

The FISH test uses fluorescent probes to attach to specific sections of DNA, and under a special microscope, these probes can be visualized. This allows the lab technician to see if there are any genetic abnormalities, such as a rearrangement in the CSF1R gene.


  • Test NameFISH for CSF1R Gene Rearrangement
  • Sample TypeBlood, Bone Marrow, or Tumor Tissue
  • Preparations RequiredNo special preparation is needed for this test. However, patients should always follow any instructions given by the doctor.
  • Report Time5 days

What does the FISH for CSF1R Gene Rearrangement test detect?

This test is designed to detect rearrangements in the CSF1R gene which can be associated with certain types of cancers and blood disorders.

How is the sample for this test collected?

The sample may be collected through a blood draw, bone marrow biopsy, or tumor tissue biopsy, depending on the patient’s condition and doctor’s recommendation.

Home Sample Collection Process
1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

The presence of CSF1R gene rearrangement can be indicative of an underlying hematologic disorder or cancer. Further diagnostic testing and consultation with a doctor are necessary to understand the implications of this finding.

This test is performed to help diagnose certain types of cancer and blood disorders, to understand the genetic characteristics of a tumor, or to guide treatment decisions.

No special preparation is needed for this test. However, it is advisable to follow any specific instructions provided by your doctor.

The quality of the sample and technical aspects of the test procedure can affect the results. It's important to have the test performed in a reputable laboratory.

The risks associated with blood draw are minimal and may include slight pain or bruising at the site of the needle insertion. For a bone marrow or tissue biopsy, there may be discomfort and a slight risk of infection.

The results can be used in the diagnosis of certain conditions, in assessing prognosis, and in making treatment decisions, especially in cases where targeted therapies against CSF1R abnormalities are available.

If the test detects a CSF1R gene rearrangement, it’s important to discuss the results with your doctor to understand what they mean in the context of your health and to determine the next steps.

This test is not commonly performed on the general population but is usually ordered for patients with specific symptoms or diagnoses that warrant investigation of CSF1R gene status.

Coverage for this test may vary depending on your insurance plan. It is advisable to consult with your insurance company before undergoing the test.

It usually takes between 7 to 14 days to get the results, but this may vary depending on the laboratory.

The CSF1R gene rearrangement can sometimes provide information about the aggressiveness of a tumor or the prognosis of a blood disorder. Your doctor will interpret the test results in the context of other clinical information.

The safety and necessity of this test during pregnancy should be discussed with your doctor.

If the test result is abnormal, it is important to consult a hematologist or oncologist who specializes in the treatment of blood disorders and cancer.

The FISH for CSF1R Gene Rearrangement is an important diagnostic tool that can provide critical information for the diagnosis and treatment of certain cancers and blood disorders. Understanding the status of the CSF1R gene can help guide treatment decisions, especially in cases where targeted therapies might be an option. As with any diagnostic test, it is important to discuss the results and implications with your doctor, who can provide expert guidance on the best course of action based on your specific health situation.

FISH for CSF1R gene rearrangement
₹ 4900
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