FISH for 6 Markers Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No special preparation is required before the test.

₹ 20000


Fluorescence In Situ Hybridization (FISH) for 6 markers is an advanced genetic testing technique that uses fluorescent probes to detect specific DNA sequences in chromosomes. This technique is particularly useful for diagnosing and monitoring a variety of genetic disorders and cancers by examining six different genetic markers simultaneously.

FISH is an established method for studying chromosomal abnormalities at the molecular level. It uses fluorescent probes that bind to specific DNA sequences in chromosomes. When viewed under a fluorescence microscope, these probes glow, revealing the presence or absence of particular DNA sequences.

In FISH for 6 markers, six distinct probes are used, allowing for the simultaneous analysis of six different chromosomal regions or sequences. This multifaceted approach is crucial when dealing with complex genetic conditions where multiple chromosomal abnormalities may be present. By assessing the interactions and relationships between different chromosomal features, FISH for 6 markers offers a comprehensive understanding of the underlying genetic anomalies.

Test Name Fluorescence In Situ Hybridization (FISH) for 6 Markers
Sample Type Blood, Bone Marrow
Preparations Required No special preparation is required before the test.
Report Time 5 days
Price in Hyderabad ₹ 20000

What is FISH for 6 markers?

FISH for 6 markers is an advanced molecular diagnostic technique that employs six different fluorescent probes to detect and visualize specific DNA sequences or chromosomal regions within cells simultaneously.

What is the significance of FISH for 6 markers?

This technique is vital for diagnosing and monitoring complex genetic disorders and cancers involving multiple genetic alterations. By examining six genetic markers at once, it provides more detailed information than traditional FISH tests, aiding in accurate diagnosis and treatment planning.

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How is FISH for 6 markers performed?

A sample, usually blood, bone marrow, or tissue, is prepared on a glass slide. The slide is then treated with six fluorescent probes that bind to specific DNA sequences. The sample is observed under a fluorescence microscope to detect the presence or absence of targeted sequences.

Who should consider having FISH for 6 markers performed?

Individuals suspected of having genetic disorders or cancers involving multiple chromosomal abnormalities should consider this test. It's also useful for monitoring the progression and response to treatment of known genetic conditions.

Is there any specific preparation required before undergoing FISH for 6 markers?

No special preparation is needed. However, it’s important to inform your doctor of any medications or supplements you are taking.

Is fasting necessary for this test?

No, fasting is not required for FISH for 6 markers.

What genetic abnormalities can be detected by FISH for 6 markers?

FISH for 6 markers can detect a range of genetic abnormalities including deletions, duplications, translocations, and inversions. It's particularly effective for complex cases where multiple genetic regions need to be analyzed.

How are the results interpreted?

A specialist, usually a geneticist or oncologist, will interpret the results based on the patterns of fluorescence observed under the microscope.

What are the benefits of using FISH for 6 markers over conventional FISH?

FISH for 6 markers allows for a more comprehensive analysis by examining six genetic regions simultaneously. This is particularly beneficial in complex cases, as it provides more detailed information for diagnosis and management.

Are there any limitations to this test?

Yes, FISH for 6 markers is highly specific and can only detect the genetic sequences for which the probes have been designed. It cannot identify unexpected mutations or genetic abnormalities outside the target regions.

How reliable are the results?

The results are highly reliable, but it's important to have them interpreted by a specialist who can consider the broader clinical context.

Which doctor should I consult if my test results are abnormal?

If your test results are abnormal, it's essential to consult a geneticist or oncologist, who specializes in the diagnosis and treatment of genetic disorders and cancers.

How often should I be tested?

The frequency of testing varies depending on the condition being monitored and the individual patient. Your doctor will provide guidance on how often the test should be performed.

What factors can affect the results?

Technical issues such as poor probe binding, sample degradation, or recent treatments such as chemotherapy can affect the results.

What do the results mean for my treatment or management?

The results from FISH for 6 markers can be used to make decisions regarding diagnosis, prognosis, and treatment options. Depending on the findings, your doctor may recommend medication, monitoring, or further genetic testing.

FISH for 6 markers is an advanced diagnostic technique that enables the simultaneous analysis of six chromosomal regions or sequences. This multiplex approach provides a comprehensive overview of the genetic landscape, which is invaluable in the diagnosis and management of complex genetic disorders and cancers. It is important to communicate with your doctor about the implications of the test results and the appropriate steps for management and treatment.

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