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FISH for 3q (TERC)

FISH for 3q (TERC)

Fluorescence In Situ Hybridization (FISH) for 3q (TERC) is a sophisticated laboratory test used to detect alterations in the 3q arm of chromosome 3, specifically focusing on the TERC gene. This test is mainly used in the field of oncology, especially in the diagnosis and management of cervical cancer and precancerous conditions. The TERC gene is essential for the maintenance of telomeres, and alterations in this gene have been linked to the progression of cervical dysplasia to invasive cervical cancer.

Chromosomal region 3q, particularly the TERC gene, has been found to be amplified in many cervical cancer cases. Identifying the amplification of TERC through FISH can help in early detection, risk assessment, and management of cervical dysplasia and cancer.


  • Test NameFISH for 3q (TERC)
  • Sample TypeCervical scrappings/Genit al swabs
  • Preparations RequiredThere are no specific preparations needed for the patient. However, it's essential to follow the doctor's instructions regarding the sample collection procedure.
  • Report Time8 Hours

What is FISH for 3q (TERC)?

FISH for 3q (TERC) is a diagnostic test that uses fluorescent probes to detect changes in the TERC gene located on the long arm (q) of chromosome 3. It is mainly used to identify alterations associated with cervical cancer.

Why is the FISH for 3q (TERC) test performed?

This test is performed to detect early chromosomal changes that are associated with the progression of cervical dysplasia to cervical cancer. It helps in risk assessment and guides treatment decisions for patients with cervical abnormalities.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

The test is performed on tissue or cell samples, usually obtained from a cervical biopsy or a Pap smear. Fluorescent probes are used to bind to the TERC gene. Under a fluorescence microscope, the appearance of fluorescence in the TERC region indicates an alteration.

An increased signal of TERC indicates amplification of the gene, which is associated with an increased risk of progression to cervical cancer. The results should be interpreted in conjunction with other clinical and diagnostic information.

There is no specific preparation required for the patient. However, it's essential to follow the doctor's instructions regarding the sample collection procedure.

The risks are primarily associated with the sample collection procedure, which may include discomfort, bleeding, and infection. The FISH test itself is performed on the collected sample and does not pose any risk to the patient.

Treatment options depend on the stage of cervical dysplasia or cancer and may include surveillance, surgery, radiation therapy, or chemotherapy. A multidisciplinary approach involving a gynecologist, oncologist, and other specialists is often employed.

Yes, lifestyle changes such as quitting smoking, practicing safe sex, and regular screening can reduce the risk of progression of cervical dysplasia to cervical cancer.

If the test results are abnormal, it is advisable to consult a gynecologist or oncologist specializing in cervical cancer.

The frequency of this test is based on the doctor's recommendations, which depend on various factors such as the patient's medical history, stage of dysplasia, and other risk factors.

Medications do not typically affect the genetic features of the cells and thus are not likely to affect the results of this test.

The costs for the FISH for 3q (TERC) test can vary. It's important to check with your health insurance and hospital regarding the expenses.

Yes, the test is available in many countries around the world. However, it's advisable to check with local healthcare providers regarding availability.

While the amplification of TERC is primarily associated with cervical cancer, research is ongoing, and the test may have potential applications in other cancers.

No, this test requires a tissue sample which needs to be obtained in a clinical setting by a medical professional, and the test itself requires sophisticated laboratory equipment.

The FISH for 3q (TERC) test is an essential tool for early detection and management of cervical cancer. By identifying alterations in the TERC gene, doctors can make informed decisions regarding the treatment and management of patients with cervical abnormalities. It is important to discuss the implications of the test results with the doctor to understand the best course of action. Regular screening and appropriate lifestyle choices play a vital role in preventing and managing cervical cancer.

FISH for 3q (TERC)
₹ 13000
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Locations Near You in Hyderabad
  • 4KM from Madhapur
  • 3KM from Banjara Hills
  • 1.9KM from Yusufguda
  • 3KM from Madhura Nagar
  • 5KM from Shaikpet