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Factor V Leiden - Mutation Detection - PCR

Factor V Leiden - Mutation Detection - PCR

Factor V Leiden is a genetic mutation that causes an increased risk of developing blood clots. The mutation makes blood clot more easily, which can be a concern as blood clots can cause life-threatening conditions such as deep vein thrombosis (DVT), pulmonary embolism, or stroke. PCR (Polymerase Chain Reaction) is a technique used in molecular genetics to detect the presence of the Factor V Leiden mutation in an individual's DNA from a blood sample.

This test is vital in assessing the risk of blood clotting disorders, particularly in individuals with a family history of such conditions or those who have experienced unexplained blood clotting events. Detecting the presence of Factor V Leiden mutation helps in managing and making decisions about treatment and preventive measures to reduce the risk of blood clots.

  • Test NameFactor V Leiden - Mutation Detection - PCR
  • Sample TypeBlood
  • Preparations RequiredNo fasting is required.
  • Report Time3 days
What is the Factor V Leiden mutation?

Factor V Leiden is a genetic mutation that causes Factor V, a protein involved in blood clotting, to be more resistant to being turned off. As a result, individuals with this mutation are at higher risk for excessive blood clotting.

What is PCR and why is it used in detecting Factor V Leiden?

PCR (Polymerase Chain Reaction) is a laboratory technique used to make millions of copies of a specific DNA segment. It's used in detecting Factor V Leiden mutation because it can amplify the mutated gene segment, making it easier to analyze.

Home Sample Collection Process

1
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2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Frequently Asked Questions

Detecting Factor V Leiden mutation is essential for assessing the risk of blood clotting disorders. Individuals with this mutation may need specific management strategies to prevent blood clots and related complications.

The mutation increases the risk of excessive blood clotting, which can lead to deep vein thrombosis, pulmonary embolism, stroke, or other clotting disorders.

Factor V Leiden is relatively common among people of European descent, affecting about 5% of this population. It is less common in other ethnic groups.

Symptoms may include swelling, pain or tenderness in the limbs, chest pain, shortness of breath, or unexplained discomfort. Some individuals may not exhibit symptoms until a significant clotting event occurs.

No, there are other genetic factors and mutations that can contribute to clotting disorders. Factor V Leiden is one of the most common ones.

Not necessarily. Having the mutation increases the risk, but other factors such as lifestyle, additional genetic factors, and medical history also play a role.

There is no cure for the genetic mutation, but the clotting disorders associated with it can be managed through medications and lifestyle changes.

Anticoagulant medications, such as warfarin or heparin, are often used to prevent blood clots in individuals with Factor V Leiden.

Maintaining a healthy weight, exercising regularly, not smoking, and following a balanced diet can help manage the risks associated with Factor V Leiden.

Yes, it’s advisable to test close family members as Factor V Leiden is a genetic mutation and can be passed down through families.

Normal values indicate no mutation in the Factor V gene. A positive result indicates the presence of Factor V Leiden mutation.

You should consult a hematologist or your primary care doctor for guidance and management of clotting disorders associated with Factor V Leiden mutation.

There are no specific precautions, but it’s crucial to inform your doctor of any medications or supplements you are taking.

Being aware of your genetic predisposition to clotting disorders through Factor V Leiden Mutation Detection can be life-saving. Understanding your risk can enable you and your doctor to take steps to prevent blood clots and related complications. If you have a family history of clotting disorders or have experienced unexplained clotting events, it's essential to discuss the possibility of Factor V Leiden mutation with your doctor. Regular monitoring and proper management can greatly reduce the risks associated with this mutation.

FACTOR V LEIDEN MUTATION, EDTA WHOLE BLOOD
₹ 6100
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