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Factor II (Prothrombin) Activity

Factor II (Prothrombin) Activity

Factor II, also known as prothrombin, is an essential protein in the blood that plays a critical role in the clotting process. It is a precursor to thrombin, which is a key enzyme that converts fibrinogen to fibrin – the primary component of blood clots. The Factor II Activity test measures the level and functionality of prothrombin in the blood, and it is a crucial test for evaluating the blood's ability to clot properly.

Factor II activity can be affected by various factors, including genetic mutations, liver disease, vitamin K deficiency, and the use of certain medications such as anticoagulants. Abnormal levels of Factor II can result in excessive bleeding or clotting disorders. The test is essential in diagnosing and managing conditions such as deep vein thrombosis, pulmonary embolism, and Factor II deficiency, which is a rare bleeding disorder.


  • Test NameFactor II (Prothrombin) Activity
  • Sample TypeBlood
  • Preparations RequiredNo fasting is necessary.
  • Report Time24 hours

What is Factor II Activity test?

Factor II Activity test measures the level and functionality of prothrombin, a protein in the blood that is crucial for the clotting process.

Why is this test important?

This test is important to evaluate the blood's ability to clot properly. It can help diagnose clotting disorders or excessive bleeding and is used to monitor patients taking anticoagulant medications.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

Individuals with a history of clotting disorders, unexplained bleeding, or those who are on anticoagulant therapy should get this test. It may also be recommended for individuals with a family history of clotting disorders.

Increased Factor II activity can lead to blood clots, while decreased activity can result in excessive bleeding. Your doctor will interpret the results in the context of your medical history and other test results.

A blood sample is drawn from a vein in the arm. The blood is then analyzed in a laboratory to measure the Factor II activity.

The risks are minimal and include slight pain or bruising at the site where the needle is inserted. There is also a very small risk of infection.

Yes, certain medications, especially anticoagulants, can affect Factor II levels. It's important to inform your doctor about any medications you are taking.

Factor II deficiency is a rare bleeding disorder caused by a lack of prothrombin. It can lead to excessive bleeding and easy bruising.

Treatment depends on the severity of the condition and may include vitamin K supplements and blood clotting factor replacement therapy.

Symptoms of abnormal Factor II activity include unexplained bleeding, blood clots, bruising, and, in severe cases, hemorrhage.

No special preparation is needed. However, it's important to inform your doctor about any medications or supplements you are taking.s

There are no dietary restrictions, but it’s essential to maintain a balanced diet as Vitamin K, found in leafy greens, plays a role in prothrombin production.

Medications, liver disease, vitamin K levels, and genetic factors can affect Factor II levels.

If your test results are abnormal, it is important to follow up with your doctor, who will provide further guidance and treatment options if necessary.

This test may be performed as a one-time evaluation or may be repeated if you are being monitored for a clotting disorder or are taking certain medications.

Factor II Activity is a critical aspect of the blood's clotting process. Understanding your Factor II Activity levels can be crucial for diagnosing and managing bleeding or clotting disorders. If you have a history of these disorders, are experiencing unexplained bleeding, or are taking anticoagulants, it’s important to talk with your doctor about whether this test is appropriate for you.

PROTHROMBIN (FACTOR II) MUTATION, EDTA WHOLE BLOOD
₹ 6700
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