Erythrocyte Sedimentation Rate (ESR), commonly known as sed rate, is a blood test used to detect inflammation in the body. This useful diagnostic tool uses Westergren's technique as the widely accepted standard to quantify the rate at which red blood cells sink at the bottom of a test tube over a one-hour period.
The ESR test assesses the rate at which red blood cells (erythrocytes) settle. The Westergren's method is one of the most common methods used for measuring ESR and is considered the standard method. This test can be a useful method for diagnosing and monitoring various conditions such as infections, autoimmune diseases, and cancers.
A blood sample is analysed in a tall, thin test tube during an ESR test, and the rate of red blood cell settlement is observed. Red blood cells settle slowly under normal conditions, but inflammation causes them to clump together, increasing the settling process. ESR is very useful in detecting and monitoring inflammatory diseases such as polymyalgia rheumatica, rheumatoid arthritis, and systemic lupus erythematosus. While this test has long been used in medical settings, its lasting significance stems from its simplicity and effectiveness. It functions as a general screening tool, encouraging additional research when abnormal values are detected.
This test evaluates how far red blood cells pass through a test tube in one hour (in millimetres). When there is inflammation, some proteins cause red blood cells to stick together and fall faster than normal.
The ESR test is frequently used to help in the diagnosis of inflammatory disorders such as arthritis or vasculitis. It is also useful for tracking the progression of inflammatory diseases.
Normal values can range from 0-29 mm/hr for women and 0-22 mm/hr for men. However, normal ranges might vary slightly depending on the laboratory that analyzes the blood sample.
No, fasting is not required for the ESR test.
If you are experiencing symptoms of an inflammation illness, a physician may recommend an ESR. The signs you have can differ depending on the disease, however they may include: