Eosinophilic Leukemia Panel - Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No special preparation is required for this test. However, it is always a good practice to inform your doctor of any medications, vitamins, or supplements you are taking.

₹ 11900


The Eosinophilic Leukemia Panel with FISH (Fluorescence In Situ Hybridization) for PDGFRA, PDGFRB, and FGFR1 is a specialized diagnostic test that aims to identify genetic abnormalities associated with eosinophilic leukemia. Eosinophilic leukemia is a rare form of blood cancer where the bone marrow produces too many eosinophils, a type of white blood cell that helps fight infections and plays a role in allergic reactions. In this condition, the eosinophils are abnormal and can accumulate in the blood and various organs, causing damage.

The panel looks for abnormalities in the PDGFRA, PDGFRB, and FGFR1 genes, which are often associated with eosinophilic leukemia. Identifying these genetic changes can be crucial for diagnosis, selecting appropriate treatment, and monitoring the disease.

Test Name Eosinophilic Leukemia Panel - FISH for PDGFRA, PDGFRB, and FGFR1
Sample Type Blood/Bone Marrow
Preparations Required No special preparation is required for this test. However, it is always a good practice to inform your doctor of any medications, vitamins, or supplements you are taking.
Report Time 5 days
Price in Hyderabad ₹ 11900

What is FISH and how does it help in diagnosing eosinophilic leukemia?

Fluorescence In Situ Hybridization (FISH) is a molecular technique that uses fluorescent probes to detect specific DNA sequences in cells. In the context of eosinophilic leukemia, it helps in identifying genetic changes in PDGFRA, PDGFRB, and FGFR1 genes which are commonly associated with this disease.

Why is it important to detect genetic changes in eosinophilic leukemia?

Detecting genetic changes can help in confirming the diagnosis, determining the prognosis, and guiding treatment decisions. Some genetic changes may be associated with sensitivity or resistance to certain therapies.

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How is the sample for this test collected?

A sample of blood or bone marrow is collected. For blood, a regular blood draw from the arm is performed. For bone marrow, a special needle is inserted into the bone to withdraw marrow.

What do PDGFRA, PDGFRB, and FGFR1 genes do?

These genes are involved in cell growth and division. Changes in these genes can lead to the uncontrolled growth of eosinophils, contributing to the development of eosinophilic leukemia.

What should I do if the test shows genetic abnormalities?

If genetic abnormalities are detected, it is essential to consult with your doctor, who will guide you through the next steps, which may include further testing, monitoring, or treatment options.

Are there any risks associated with this test?

The blood draw is generally safe with minimal risks. Bone marrow aspiration carries risks like infection and bleeding, but these are generally low when performed by an experienced medical professional.

Can this test be used to monitor the progression of eosinophilic leukemia?

Yes, this test can be used to monitor the progression of the disease and to check the effectiveness of treatment by looking for changes in the levels of abnormal cells.

Are there any treatments available if I am diagnosed with eosinophilic leukemia?

Yes, there are treatments available which include chemotherapy, targeted therapy, and sometimes stem cell transplantation. The choice of treatment depends on various factors including the type of genetic abnormalities present.

Can this test predict the outcome of eosinophilic leukemia?

Yes, certain genetic changes are associated with a poorer prognosis, while others may be associated with a better response to treatment. Understanding the genetic makeup of the leukemia cells can provide valuable information regarding the likely course of the disease.

Is this test performed routinely?

This test is not performed routinely and is generally ordered when eosinophilic leukemia is suspected based on clinical symptoms and initial blood tests.

Can eosinophilic leukemia be cured?

The possibility of a cure depends on various factors including the stage of the disease, genetic makeup of the leukemia cells, and the patient’s overall health. Some patients achieve long-term remission with treatment.

Does this test replace the need for a bone marrow biopsy?

No, this test does not replace the need for a bone marrow biopsy. It is often used in conjunction with a bone marrow biopsy for a comprehensive evaluation.

What is the role of a hematologist in eosinophilic leukemia?

A hematologist is a doctor who specializes in blood disorders, including leukemia. They are instrumental in diagnosing, treating, and monitoring patients with eosinophilic leukemia.

Can eosinophilic leukemia be prevented?

Currently, there is no known way to prevent eosinophilic leukemia as the exact cause is not known.

Is this test covered by insurance?

Coverage for this test depends on your insurance plan. It is recommended to check with your insurance provider regarding coverage.

The Eosinophilic Leukemia Panel - FISH for PDGFRA, PDGFRB, and FGFR1 is a valuable diagnostic tool that aids in the identification of genetic abnormalities associated with eosinophilic leukemia. This information can be critical in guiding treatment decisions and monitoring the course of the disease. If you or a loved one have been diagnosed with or are suspected of having eosinophilic leukemia, it's important to discuss with a doctor the benefits of undergoing this testing.

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