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Lab Test

CYP2C19 Genotyping Test

CYP2C19 genotyping is a genetic test that evaluates specific inherited variations in the CYP2C19 gene to determine how an individual might metabolize or respond to certain medications, notably clopidogrel, which is an antiplatelet medication commonly used to prevent heart attacks and strokes in individuals with heart disease. The CYP2C19 enzyme, encoded by the CYP2C19 gene, plays a significant role in the activation of clopidogrel. Variations in the CYP2C19 gene can influence the enzyme’s activity, affecting how well clopidogrel is activated and consequently, how effective it is in preventing blood clots.


  • Test Name CYP2C19 Genotyping (Clopidogrel Gene Mutation / Clopidogrel Resistance) Test
  • Sample Type Blood
  • Preparations Required No special preparation is needed for this test.
  • Report Time 8 days

Understanding how an individual’s genetic makeup influences the response to clopidogrel can help doctors determine the most effective and safest medication regimens for patients who need antiplatelet therapy. This personalized approach to medication, known as pharmacogenomics, can improve drug efficacy and minimize adverse effects.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

CYP2C19 genotyping is a genetic test that analyzes variations in the CYP2C19 gene to predict how an individual will respond to certain medications, including the antiplatelet drug clopidogrel.

This test is important for determining how effectively a person can convert clopidogrel to its active form. The results can guide doctors in prescribing the best medication and dosage to prevent blood clots in patients with heart disease.

A blood sample is drawn from your arm and sent to a laboratory where it is analyzed for specific genetic variations in the CYP2C19 gene.

No, there is no need for fasting or any special preparation for the CYP2C19 genotyping test.

If you have a CYP2C19 gene mutation, it may mean that your body cannot effectively convert clopidogrel to its active form, potentially making the drug less effective at preventing blood clots.

Your doctor will use the results to personalize your treatment. Based on your CYP2C19 genotype, they may adjust the dosage of clopidogrel or choose an alternative medication.

The test itself has minimal risks, similar to those of a routine blood draw. The information obtained can be vital in guiding treatment decisions and minimizing adverse drug reactions.

No, while it's frequently used for clopidogrel therapy, CYP2C19 genotyping can also impact the use of other medications. The enzyme is involved in the metabolism of various drugs.

If you have a mutation in the CYP2C19 gene, it's advisable to discuss the results with a cardiologist or a doctor who is managing your antiplatelet therapy.

CYP2C19 genotyping is usually a one-time test since your genes do not change over time.

There are no “normal” values for CYP2C19 genotyping. The test identifies specific genetic variations, and results are generally categorized as poor, intermediate, extensive, or ultra-rapid metabolizers.

Genetic tests like CYP2C19 genotyping are quite reliable, and there are not many factors that would affect the results. However, laboratory errors can occur.

Non-modifiable factors include genetic variations in the CYP2C19 gene. Modifiable factors can include adherence to medication, interactions with other medications, and lifestyle factors such as diet.

Coverage for the CYP2C19 genotyping test varies among health insurance plans. It's advisable to check with your insurance company to see if they cover the test.

If you have additional questions or concerns about the CYP2C19 genotyping test, it’s best to discuss them with your doctor, who can provide detailed information and guidance based on your specific health condition.

Understanding your genetic makeup, especially how it affects drug metabolism, can be crucial in managing conditions like heart disease. CYP2C19 genotyping helps to personalize treatment plans, ensuring that patients receive the most effective and safest therapeutic options. If you have been prescribed clopidogrel or are considering antiplatelet therapy, discussing CYP2C19 genotyping with your doctor can be an important step in optimizing your treatment.

CYP2C19 GENOTYPING (Clopidogrel gene mutaion / Clopidogrel resistance)
₹ 7000
Schedule Test in Your Available Time
Locations Near You in Hyderabad
  • 4KM from Madhapur
  • 3KM from Banjara Hills
  • 1.9KM from Yusufguda
  • 3KM from Madhura Nagar
  • 5KM from Shaikpet