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Lab Test

Cryptococcus Antigen Detection

Cryptococcus is a fungus that can cause infections primarily in people with weakened immune systems. The most common form of infection is cryptococcal meningitis, which is an infection of the membranes surrounding the brain and spinal cord. The Cryptococcus Antigen Detection test is critical in identifying the presence of Cryptococcus. In cases where this test is negative but there is still a high suspicion of infection, reflexing to a CSF fungal culture is essential to rule out Cryptococcus and identify any other fungal infection that might be present.


  • Test Name Cryptococcus Antigen Detection
  • Sample Type CSF (Cerebrospinal Fluid)
  • Preparations Required No specific preparation is required for this test.
  • Report Time Culture: PRELIM 7th day, FINAL 21st day, Antigen Detection : Same day

CSF fungal culture involves the cultivation of cerebrospinal fluid in a medium that encourages the growth of fungi. It is used to detect fungal infections in the central nervous system. Cryptococcal meningitis is potentially life-threatening, especially in immunocompromised individuals, making early detection and treatment crucial for the patient's prognosis.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

This test is vital in detecting Cryptococcus infections early, especially cryptococcal meningitis, which can be life-threatening. Early detection facilitates timely treatment, improving the chances of recovery.

If the Cryptococcus Antigen Detection is negative but there is still suspicion of an infection, the sample is reflexed to a CSF fungal culture. This culture helps to rule out Cryptococcus and may identify other fungal infections.

Individuals with symptoms of meningitis or those who are at high risk, especially people with weakened immune systems, such as HIV/AIDS patients, should consider this test.

No, fasting is not required for this test.

The sample is collected by a lumbar puncture, where a needle is inserted into the lower back to collect cerebrospinal fluid.

A positive test indicates the presence of Cryptococcus, which suggests an active infection.

Besides Cryptococcus, a CSF fungal culture can detect other fungi such as Candida, Aspergillus, and Histoplasma.

It typically takes between 2 to 5 days to get the results, as the sample needs to be cultured in a lab to check for fungal growth.

Symptoms include headache, fever, neck stiffness, nausea, vomiting, light sensitivity, and altered mental status.

Treatment usually involves antifungal medications. The specific drugs and duration of treatment depend on the severity of the infection and the patient's health.

Though generally safe, lumbar puncture can sometimes cause headaches, bleeding, or infection at the puncture site. It is important to follow the doctor’s instructions before and after the procedure.

If the test result is abnormal, consulting your doctor is advised. You may be referred to an infectious disease specialist for further evaluation and management.

People with weakened immune systems should avoid environments where Cryptococcus is commonly found, such as soil contaminated with bird droppings. Regular medical check-ups and taking medications as prescribed also help in preventing infections.

Early detection of Cryptococcus infections is vital, especially for individuals with weakened immune systems. The Cryptococcus Antigen Detection Test, along with a reflex to CSF fungal culture when necessary, plays a critical role in timely diagnosis and management. If you have symptoms suggestive of cryptococcal meningitis or are at high risk, it is essential to consult your doctor and discuss the need for testing. Proper adherence to treatment regimens and preventive measures are key to mitigating the risks associated with Cryptococcus infections.

Cryptococcus Antigen Detection If Negative Reflex CSF Fungal Culture
₹ 2600
Schedule Test in Your Available Time
Locations Near You in Hyderabad
  • 4KM from Madhapur
  • 3KM from Banjara Hills
  • 1.9KM from Yusufguda
  • 3KM from Madhura Nagar
  • 5KM from Shaikpet