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Lab Test

Creatine Kinase (CPK) - Isoenzymes Electrophoresis Test

The Creatine Kinase (CPK) - Isoenzymes Electrophoresis Test is a blood test that measures the levels of different forms of creatine kinase, an enzyme found in various tissues in the body including the heart, brain, and skeletal muscles. The test is crucial in diagnosing and monitoring muscle diseases, heart attacks, and other conditions where muscle damage may occur. By analyzing the isoenzymes of CPK through electrophoresis, this test helps in pinpointing the source of muscle damage.


  • Profile Name: Creatine Kinase (CPK) - Isoenzymes Electrophoresis Test
  • Sample Type: Blood
  • Preparations Required: No strenuous physical activity for 24 hours before the test.
  • Report Time: 2 Days

What is the Creatine Kinase (CPK) - Isoenzymes Electrophoresis Test?

It is a blood test that measures the levels of different forms of creatine kinase, an enzyme that plays a role in energy production in muscles. The isoenzymes help in identifying the specific tissues that are damaged.

Why is the CPK - Isoenzymes Electrophoresis Test performed?

This test is performed to diagnose muscle diseases, to determine if there is muscle damage after a heart attack, or to monitor muscle damage in other conditions.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

A healthcare professional will take a blood sample from a vein in your arm. The sample is then sent to a laboratory, where the levels of CPK isoenzymes are measured through electrophoresis.

Elevated levels of specific CPK isoenzymes indicate damage to certain tissues. For example, high levels of CPK-MB suggest heart muscle damage, while high levels of CPK-MM indicate skeletal muscle damage.

Normal ranges can vary, but typically, CPK-MM should make up 95-100% of total CPK, CPK-MB should be 0-5%, and CPK-BB should be 0%.

The risks are minimal and are similar to those associated with any blood draw, such as pain, bruising, or infection at the injection site.

Avoid any strenuous physical activity for 24 hours before the test, as it can affect the levels of CPK isoenzymes in your blood.

Consult your primary care doctor if your CPK isoenzymes levels are abnormal. They may refer you to a cardiologist or a rheumatologist depending on the findings.

Yes, certain medications such as statins, steroids, and some psychiatric medications can affect CPK levels.

Yes, the CPK-MB isoenzyme is particularly important in diagnosing heart muscle damage, which occurs during a heart attack.

Electrophoresis is a laboratory technique used to separate proteins based on their size and electrical charge. It helps in analyzing different forms of a single protein, such as CPK isoenzymes.

Yes, strenuous exercise can cause muscle damage, which can elevate CPK levels, particularly the CPK-MM isoenzyme.

Creatine kinase plays a crucial role in energy production in muscles. It helps in converting creatine into phosphocreatine, which is used as a source of energy for muscle contractions.

Yes, this test is useful in diagnosing and monitoring muscle diseases such as muscular dystrophy and polymyositis.

Yes, factors such as recent intramuscular injections, trauma, surgery, and certain medications can interfere with the test results.

The Creatine Kinase (CPK) - Isoenzymes Electrophoresis Test is a highly valuable tool for diagnosing and monitoring conditions involving muscle damage. Whether the concern is a heart attack, muscle disease, or other muscle-related conditions, this test provides vital information for effective management and treatment. It is essential to consult a doctor for proper interpretation of test results and appropriate next steps.

Creatine Kinase(CPK) - isoenzymes Electrophoresis
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