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Lab Test

Cortisol Suppression by Dexamethasone, Overnight Low Dose Test

The Cortisol Suppression by Dexamethasone, Overnight Low Dose Test, often known as the Low Dose Dexamethasone Suppression Test, is used to evaluate the adrenal glands' function by measuring how well they respond to the drug dexamethasone. This test is particularly beneficial in diagnosing disorders associated with excessive cortisol levels, such as Cushing's syndrome.


  • Profile Name: Cortisol Suppression by Dexamethasone, Overnight Low Dose Test
  • Sample Type: Blood
  • Preparations Required: The test requires taking a low dose of dexamethasone, usually at 11 p.m., and having blood drawn the next morning at 8 a.m. Follow the doctor's instructions for taking dexamethasone, and avoid additional medications unless approved by the doctor.
  • Report Time: 6 hours

Cortisol is a hormone produced by the adrenal glands, situated above the kidneys. It plays a vital role in metabolism, immune response, blood pressure regulation, and stress response. Dexamethasone is a medication that mimics the effects of cortisol and typically suppresses its production in healthy individuals. In this test, a low dose of dexamethasone is administered, and cortisol levels are measured the following morning.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

This test involves taking a low dose of dexamethasone to suppress cortisol production and measuring cortisol levels in the blood the next morning. It helps diagnose disorders related to excessive cortisol, such as Cushing's syndrome.

You will take a low dose of dexamethasone, usually at 11 p.m., and then have blood drawn the next morning at 8 a.m. to measure cortisol levels.

This test is important for diagnosing disorders that involve abnormal cortisol production, such as Cushing's syndrome. Early diagnosis is essential for managing symptoms and preventing complications.

If cortisol levels do not decrease significantly after taking dexamethasone, it may indicate the presence of Cushing's syndrome or another disorder affecting cortisol production.

The risks are minimal and may include slight pain or bruising at the blood draw site. There may also be side effects from taking dexamethasone, such as nausea or difficulty sleeping.

Follow your doctor’s instructions for taking dexamethasone and avoid taking other medications unless approved by your doctor. Be prepared for blood to be drawn at the specified time.

Yes, certain medications, especially corticosteroids, can affect cortisol levels. Inform your doctor about all medications and supplements you are taking.

You should consult an endocrinologist in case of abnormal test results.

Symptoms of Cushing's syndrome may include weight gain, fatty deposits around the face and midsection, thinning skin, easy bruising, and muscle weakness.

Yes, this test can be used to monitor changes in cortisol levels and evaluate the effectiveness of treatments for Cushing's syndrome.

Normally, cortisol levels should be suppressed after taking a low dose of dexamethasone. However, normal ranges can vary, so it’s important to discuss the results with your doctor.

There are no dietary restrictions, but it's best to follow a normal diet and avoid excessive consumption of caffeinated beverages. You should also stay hydrated.

In addition to the low dose dexamethasone suppression test, other tests such as the 24-hour urinary free cortisol test, late-night salivary cortisol test, and high-dose dexamethasone suppression test may be used.

Treatment for Cushing's syndrome depends on the underlying cause and may include surgery to remove tumors, radiation therapy, medications to control cortisol production, and lifestyle changes.

The Cortisol Suppression by Dexamethasone, Overnight Low Dose Test is a valuable tool for diagnosing and managing conditions related to abnormal cortisol production, particularly Cushing's syndrome. Proper preparation for the test and following the doctor's instructions are crucial. Understanding the significance of this test and discussing the results and treatment options with your doctor can lead to better management of your health and well-being.

Cortisol Suppression by Dexamethasone, Overnight Low Dose
₹ 1155
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  • 4KM from Madhapur
  • 3KM from Banjara Hills
  • 1.9KM from Yusufguda
  • 3KM from Madhura Nagar
  • 5KM from Shaikpet