Cortisol Suppression by Dexamethasone | Overnight Low Dose Test - Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : The test requires taking a low dose of dexamethasone, usually at 11 p.m., and having blood drawn the next morning at 8 a.m. Follow the doctor's instructions for taking dexamethasone, and avoid additional medications unless approved by the doctor.

₹ 1155


The Cortisol Suppression by Dexamethasone, Overnight Low Dose Test, often known as the Low Dose Dexamethasone Suppression Test, is used to evaluate the adrenal glands' function by measuring how well they respond to the drug dexamethasone. This test is particularly beneficial in diagnosing disorders associated with excessive cortisol levels, such as Cushing's syndrome.

Cortisol is a hormone produced by the adrenal glands, situated above the kidneys. It plays a vital role in metabolism, immune response, blood pressure regulation, and stress response. Dexamethasone is a medication that mimics the effects of cortisol and typically suppresses its production in healthy individuals. In this test, a low dose of dexamethasone is administered, and cortisol levels are measured the following morning.

Test Name Cortisol Suppression by Dexamethasone, Overnight Low Dose Test
Sample Type Blood
Preparations Required The test requires taking a low dose of dexamethasone, usually at 11 p.m., and having blood drawn the next morning at 8 a.m. Follow the doctor's instructions for taking dexamethasone, and avoid additional medications unless approved by the doctor.
Report Time 6 hours
Price ₹ 1155

What is the Cortisol Suppression by Dexamethasone, Overnight Low Dose Test?

This test involves taking a low dose of dexamethasone to suppress cortisol production and measuring cortisol levels in the blood the next morning. It helps diagnose disorders related to excessive cortisol, such as Cushing's syndrome.

How is this test performed?

You will take a low dose of dexamethasone, usually at 11 p.m., and then have blood drawn the next morning at 8 a.m. to measure cortisol levels.

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Why is this test important?

This test is important for diagnosing disorders that involve abnormal cortisol production, such as Cushing's syndrome. Early diagnosis is essential for managing symptoms and preventing complications.

What does it mean if cortisol levels do not decrease after taking dexamethasone?

If cortisol levels do not decrease significantly after taking dexamethasone, it may indicate the presence of Cushing's syndrome or another disorder affecting cortisol production.

Are there any risks associated with this test?

The risks are minimal and may include slight pain or bruising at the blood draw site. There may also be side effects from taking dexamethasone, such as nausea or difficulty sleeping.

How should I prepare for this test?

Follow your doctor’s instructions for taking dexamethasone and avoid taking other medications unless approved by your doctor. Be prepared for blood to be drawn at the specified time.

Can medications interfere with the results of the test?

Yes, certain medications, especially corticosteroids, can affect cortisol levels. Inform your doctor about all medications and supplements you are taking.

Which doctor should be consulted in case of abnormal test results?

You should consult an endocrinologist in case of abnormal test results.

What are some symptoms of Cushing's syndrome?

Symptoms of Cushing's syndrome may include weight gain, fatty deposits around the face and midsection, thinning skin, easy bruising, and muscle weakness.

Can the test be used to monitor the effectiveness of treatment for Cushing's syndrome?

Yes, this test can be used to monitor changes in cortisol levels and evaluate the effectiveness of treatments for Cushing's syndrome.

What are normal cortisol levels after taking a low dose of dexamethasone?

Normally, cortisol levels should be suppressed after taking a low dose of dexamethasone. However, normal ranges can vary, so it’s important to discuss the results with your doctor.

Can I eat and drink normally before the test?

There are no dietary restrictions, but it's best to follow a normal diet and avoid excessive consumption of caffeinated beverages. You should also stay hydrated.

What other tests might be used to diagnose Cushing's syndrome?

In addition to the low dose dexamethasone suppression test, other tests such as the 24-hour urinary free cortisol test, late-night salivary cortisol test, and high-dose dexamethasone suppression test may be used.

What are the treatment options for Cushing's syndrome?

Treatment for Cushing's syndrome depends on the underlying cause and may include surgery to remove tumors, radiation therapy, medications to control cortisol production, and lifestyle changes.

The Cortisol Suppression by Dexamethasone, Overnight Low Dose Test is a valuable tool for diagnosing and managing conditions related to abnormal cortisol production, particularly Cushing's syndrome. Proper preparation for the test and following the doctor's instructions are crucial. Understanding the significance of this test and discussing the results and treatment options with your doctor can lead to better management of your health and well-being.

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