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Lab Test

Cortisol Free, Urine 24 Hours Test

The Cortisol Free, Urine 24 Hours Test measures the amount of cortisol present in the urine over a 24-hour period. Cortisol is a hormone produced by the adrenal glands, located above the kidneys. It is essential for various bodily functions, including metabolism, immune response, blood pressure regulation, and the body’s response to stress.


  • Test Name Cortisol Free, Urine 24 Hours Test
  • Sample Type Urine
  • Preparations Required Avoid strenuous exercise, stress, and consumption of alcohol or caffeine for 24 hours before and during the urine collection period. Consult your doctor regarding medications as some can affect cortisol levels.
  • Report Time 24 hours

This test is particularly useful in diagnosing and managing disorders that involve abnormal cortisol levels, such as Cushing's syndrome (where the body produces too much cortisol) and Addison's disease (where the body doesn’t produce enough cortisol). By collecting urine over 24 hours, the test provides a more comprehensive picture of cortisol production as its levels can vary throughout the day.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

The Cortisol Free, Urine 24 Hours Test is a diagnostic test that measures the amount of cortisol in the urine collected over a 24-hour period to assess adrenal function and detect disorders related to cortisol levels.

You will be provided with a special container to collect your urine over a 24-hour period. All the urine passed in the 24-hour period should be collected, starting from the second voided urine after waking up. The collected sample is then sent to a laboratory for analysis.

This test is important for diagnosing and monitoring conditions that affect cortisol production, such as Cushing’s syndrome and Addison’s disease. It helps in evaluating adrenal function and the body’s response to stress over an extended period.

A high level of cortisol in the urine could indicate Cushing's syndrome, chronic stress, adrenal tumors, or excessive use of corticosteroid medications.

A low level of cortisol in the urine might suggest Addison's disease, adrenal insufficiency, or hypopituitarism.

There are no significant risks associated with collecting urine for this test. It is non-invasive and does not involve any pain or discomfort.

Avoid strenuous exercise, stress, and consumption of alcohol or caffeine for 24 hours before and during the urine collection period. Consult your doctor regarding any medications, as some can affect cortisol levels.

Yes, certain medications, especially corticosteroids, can affect cortisol levels in the urine. Inform your doctor about all medications and supplements you are taking.

In case of abnormal cortisol levels, it is advisable to consult an endocrinologist.

Modifiable factors include stress levels, physical activity, consumption of alcohol and caffeine, and the use of certain medications.

Non-modifiable factors include genetic disorders such as Cushing’s syndrome and certain diseases affecting the adrenal glands.

Cortisol is known as the "stress hormone" because it is released in response to stress and low blood glucose levels. It helps the body to mobilize energy stores and maintain blood pressure during stressful situations.

Yes, this test can be used to monitor the effectiveness of treatments for disorders such as Cushing’s syndrome and Addison’s disease by assessing changes in cortisol levels over time.

The Cortisol Free, Urine 24 Hours Test is an essential tool for evaluating adrenal function and diagnosing disorders related to cortisol levels. The test, which measures cortisol levels in urine over 24 hours, offers a comprehensive assessment of how the body is managing this critical hormone. Preparing properly for the test and consulting with your doctor for interpretation and advice based on the results is crucial in managing your health.

CORTISOL FREE, 24 HRS URINE
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