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Lab Test

Chimerism Study Post Bone Marrow Transplant

Bone marrow transplants, also known as stem cell transplants, involve replacing unhealthy bone marrow with healthy cells (stem cells). It's a standard treatment for conditions like leukemia, lymphoma, and myeloma, as well as for some types of anemia and immune deficiency diseases.


  • Profile Name: Chimerism Study Post Bone Marrow Transplant
  • Sample Type: Blood or Bone Marrow
  • Preparations Required: No fasting or specific preparation is required prior to the test.
  • Report Time: 8 Days

Following a bone marrow transplant, a Chimerism Study is often conducted. "Chimerism" refers to the presence of two genetically distinct cell types in an organism. After a transplant, both the patient's original cells and the donor's transplanted cells are present, creating a state of chimerism.

To understand the importance and implications of this study, let's explore some commonly asked questions.

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Reporting of the sample at lab
Reporting of the sample at lab
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Frequently Asked Questions

A Chimerism Study is a test used to assess the ratio of donor to recipient cells following a bone marrow transplant. It helps determine if the transplanted cells have engrafted and are producing new blood cells.

A Chimerism Study is done to monitor the success of the transplant. It helps identify if the transplant is successful and whether the new cells are growing. It also helps detect early signs of graft failure or disease relapse.

The study is performed on a sample of blood or bone marrow. The sample is then analyzed in a lab to distinguish between the patient's original cells and the donor's transplanted cells.

The frequency of the Chimerism Study post-transplant is determined by the treating physician. Typically, it's done frequently in the early stages after the transplant and then at regular intervals as determined by your doctor.

A high percentage of donor cells indicates successful engraftment, while a low percentage or decreasing percentage of donor cells over time may suggest graft failure or disease relapse.

Factors that can affect the results of a Chimerism Study include the patient's overall health, the success of the transplant, and potential complications such as infections or graft-versus-host disease (GVHD).

You should consult the hematologist or the doctor who oversees your transplant care if your Chimerism Study shows abnormal results.

The results of the Chimerism Study are typically presented as a percentage, indicating the ratio of donor cells to recipient cells in your body.

Yes, a Chimerism Study can help predict complications after a bone marrow transplant. If the proportion of donor cells is decreasing, it may indicate complications such as graft failure or disease relapse.

Risks associated with a Chimerism Study are similar to those of a standard blood draw or bone marrow biopsy, including pain, bleeding, or infection at the needle site.

The results of the Chimerism Study can guide the doctor in planning further treatment. If the transplant is not successful, or if the disease relapses, additional treatments or interventions may be necessary.

Yes, a Chimerism Study can be performed on patients of any age who've had a bone marrow transplant.

There's no specific preparation needed for a Chimerism Study. Just ensure to keep your appointment for the test and follow any instructions given by your doctor.

While the primary purpose of a Chimerism Study is to assess the success of a bone marrow transplant, it may indirectly indicate other potential health issues. For example, a decrease in the proportion of donor cells might suggest an underlying infection or disease relapse.

Most insurance providers offer coverage for necessary post-transplant monitoring tests, including the Chimerism Study. However, it's advisable to check with your insurance company for specifics about coverage and costs.

Typically, the results of a Chimerism Study are available within 3-7 days. However, the exact timeline may vary depending on the laboratory.

If the Chimerism Study indicates graft failure, your doctor might consider options such as adjusting medications, additional chemotherapy, or another bone marrow transplant. The specific plan will depend on your overall health, your response to the initial transplant, and other individual factors.

The pain associated with a Chimerism Study is similar to that of a blood draw. If a bone marrow sample is taken, you might experience a sharp but brief pain.

Yes, the results of a Chimerism Study can change over time as the balance between donor and recipient cells in your body can shift. This is why repeated studies are often done after a transplant.

No, a Chimerism Study requires a blood or bone marrow sample to be taken and analyzed in a laboratory. Therefore, it cannot be done at home.

Following a bone marrow transplant, a Chimerism Study serves as a critical tool to track the success of the procedure. It offers vital insights into whether the body is accepting the new cells and assists in detecting possible complications in a timely manner. As always, it's essential to maintain open communication with your medical team to understand the specifics of your test results and the implications for your overall treatment plan.

Chimerism Study Post Bone Marrow Transplant
₹ 7400
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  • 4KM from Madhapur
  • 3KM from Banjara Hills
  • 1.9KM from Yusufguda
  • 3KM from Madhura Nagar
  • 5KM from Shaikpet