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Book Calreticulin Mutation Test Near You in Hyderabad

Calreticulin is a protein found inside cells, primarily in the endoplasmic reticulum, where it plays a crucial role in ensuring proper protein folding and maintaining calcium balance. Mutations in the Calreticulin (CALR) gene can lead to the production of an abnormal version of this protein. These mutations are most commonly associated with certain types of myeloproliferative neoplasms, a group of diseases that cause an overproduction of blood cells.


  • Test NameCalreticulin Mutation
  • Sample TypeBlood
  • Preparations RequiredNo special preparation is needed before this test.
  • Report Time8 days

Testing for CALR mutations has become increasingly important in diagnosing and managing myeloproliferative neoplasms. These mutations are found in a significant proportion of patients with essential thrombocythemia (ET) and primary myelofibrosis (PMF), two of the most common myeloproliferative neoplasms. The presence of a CALR mutation can have implications for the disease prognosis, and it may guide treatment decisions.

Home Sample Collection Process
1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Download Reports
Frequently Asked Questions

The Calreticulin Mutation test is a genetic test that checks for mutations in the CALR gene, which can cause an overproduction of blood cells leading to certain types of myeloproliferative neoplasms.

This test is essential in diagnosing certain blood disorders like essential thrombocythemia and primary myelofibrosis. It can also provide valuable prognostic information and guide treatment decisions.

No, fasting is not required for the Calreticulin Mutation test.

This test checks for mutations in the CALR gene. These mutations can cause the production of an abnormal version of the calreticulin protein, which can lead to myeloproliferative neoplasms.

The frequency of this test is determined by your doctor based on your symptoms and medical history. If you have been diagnosed with a myeloproliferative neoplasm, the test may be performed periodically to monitor your condition.

Genetic factors are the primary determinants of CALR mutation presence. Environmental factors are generally not known to induce these specific mutations.

The normal result for the Calreticulin Mutation test is negative, meaning no mutation was detected in the CALR gene.

An abnormal result means a mutation was detected in the CALR gene. This is associated with certain types of myeloproliferative neoplasms, including essential thrombocythemia and primary myelofibrosis.

No special precautions are needed before taking a Calreticulin Mutation test.

Since CALR mutations are genetic, they cannot be changed by lifestyle or environmental factors. The presence of a mutation is determined by your genes, which you inherit from your parents.

If your test results are abnormal, you should consult with a hematologist or a medical geneticist. These specialists will interpret your results and guide the appropriate next steps, which may include further testing or treatment.

The test is performed using a blood sample. The sample is sent to a lab where the DNA is extracted and the CALR gene is analyzed for mutations.

The presence of a CALR mutation is specifically associated with certain types of myeloproliferative neoplasms, and is not generally affected by other diseases or conditions.

You should see a hematologist, who is a doctor specialized in blood disorders.

No, medications do not affect the results of a genetic test like the Calreticulin Mutation test.

The genetic changes that contribute to disease can be a powerful tool in diagnosis and treatment. The Calreticulin Mutation test provides critical information for patients with certain types of blood disorders. With this information, doctors can develop the most effective treatment plans and monitor disease progression more accurately. Always consult with your doctor if you have concerns or questions about this test.

Calreticulin Mutation
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