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C4 Diagnostic Test

C4, or Complement 4, is one of the proteins that form the complement system, which is a part of the immune system. This system contains a group of proteins that work together to help fight infections, and it also plays a role in inflammation and other immune system processes. C4 is a critical protein in the complement system. It helps in clearing microbes and the products of cell injury, and it is involved in the immune responses.


  • Test Name C4 Diagnostic Test
  • Sample Type Blood
  • Preparations Required No special preparation is required for this test.
  • Report Time 4 hours

Complement 4 (C4) test is a blood test that measures the levels of C4 in your blood. This test is often performed to see if there are abnormalities in the immune system, especially in cases of suspected autoimmune diseases. This is because the levels of complement proteins, including C4, can change when there is inflammation or when the immune system is not functioning correctly.

Home Sample Collection Process

1
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Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Frequently Asked Questions

The C4 test is primarily used to evaluate the level of the C4 protein in your blood. It's often ordered to help diagnose and monitor autoimmune diseases, like lupus or rheumatoid arthritis.

Testing C4 levels is crucial in diagnosing and monitoring autoimmune diseases. Abnormal levels might suggest an overactive immune system and ongoing inflammation. Knowing your C4 levels can help your doctor determine the most appropriate treatment for your condition.

No, fasting is not required for the C4 test. You can have your blood drawn at any time of the day without any special preparation.

A small sample of blood is drawn from a vein, usually in your arm. The blood is then sent to a laboratory where the levels of C4 in the sample are measured.

The frequency of testing depends on various factors including your medical history, any symptoms you may be experiencing, and what your doctor is looking for. Your doctor will provide the best guidance on how often you should be tested.

Normal values for C4 typically range from 16 to 48 milligrams per deciliter (mg/dL), but normal ranges can vary slightly depending on the laboratory that analyzes the blood sample.

Modifiable factors that can affect C4 levels include medication use, especially immune-suppressing drugs. Non-modifiable factors include genetics and underlying autoimmune diseases.

Low levels of C4 might indicate an overactive immune system, often seen in autoimmune diseases like lupus. It can also indicate a hereditary deficiency or consumption due to infection.

Elevated C4 levels can be a response to acute infections, inflammation, or stress. They can also occur during pregnancy or as a reaction to certain medications.

Generally, no special precautions are necessary. However, it’s important to inform your doctor about any medications or supplements you are taking as they might affect the results.

If your C4 levels are not within the normal range, it’s essential to consult a doctor for further evaluation and guidance. The doctor may request additional tests or start you on treatment depending on the results.

Yes, often doctors will order other complement tests such as C3, or tests that measure total complement activity. It might be part of a broader diagnostic plan to evaluate your immune system.

The test involves a standard blood draw, which might cause mild discomfort or bruising at the site where the needle is inserted, but generally, it's not considered painful.

Yes, C4 levels can fluctuate due to infections, medications, or other transient factors. It is important to have regular monitoring if you have an autoimmune condition or other diseases affecting the immune system.

If your C4 levels are abnormal, it is advised to consult with a doctor who specializes in immunology or rheumatology. They have specialized knowledge in diseases of the immune system and can guide you through diagnosis and treatment.

Understanding your C4 levels and their role in your immune system can be an essential aspect of managing your health. This test is particularly important for individuals with autoimmune diseases or those who have a family history of these conditions. Regular monitoring and consultation with your doctor can ensure that any issues are detected early and managed effectively.

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