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C1 Esterase Inhibitor - Functional

C1 Esterase Inhibitor, often abbreviated as C1-INH, is a protein found in the blood that plays a critical role in regulating the activation of certain components of the immune system. The functional C1 Esterase Inhibitor test is designed to assess the functional activity of this protein. This is important because certain disorders can result from the deficiency or malfunction of C1 Esterase Inhibitor, such as hereditary angioedema (HAE), which is a rare genetic disorder characterized by episodes of severe swelling in different parts of the body.

  • Test Name C1 Esterase Inhibitor - Functional
  • Sample Type Blood
  • Preparations Required No special preparation is required for this test.
  • Report Time 4 days

Home Sample Collection Process

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Book your convenient slot
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
Reporting of the sample at lab
Reporting of the sample at lab
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Download Reports
Frequently Asked Questions

C1 Esterase Inhibitor is a protein in the blood that helps control inflammation and acts as a regulator of the complement and contact systems, both part of the immune response.

This test is important for diagnosing conditions such as hereditary angioedema, where a deficiency or dysfunction of C1 Esterase Inhibitor can cause severe, recurrent swelling episodes. The test helps determine if the protein is present and functioning properly.

Hereditary Angioedema is a rare genetic disorder characterized by episodes of severe swelling, often affecting the face, extremities, airways, and intestinal tract. It is caused by a deficiency or malfunction of the C1 Esterase Inhibitor protein.

Low or non-functional C1 Esterase Inhibitor can lead to excessive activation of the complement system, resulting in recurrent episodes of angioedema, which is marked by severe swelling in different parts of the body.

The test is performed using a blood sample. A healthcare professional will draw blood from a vein, usually in your arm, and the sample will be sent to a laboratory for analysis.

No special preparation is needed for the C1 Esterase Inhibitor - Functional test. However, you should inform your doctor of any medications or supplements you are taking, as some can affect the test results.

Normal values can vary among different laboratories, but generally, the functional activity of C1 Esterase Inhibitor is expected to be within the range of 70-130% of normal.

Yes, treatment options for conditions caused by C1 Esterase Inhibitor deficiency, such as hereditary angioedema, include medications that replace the missing or non-functional protein, and medications that reduce swelling.

You should consult an immunologist or allergist if your C1 Esterase Inhibitor levels are abnormal as these specialists have experience in managing disorders related to the immune system.

No, while Hereditary Angioedema is the most common condition associated with C1 Esterase Inhibitor deficiency, there are other conditions and factors which may also be associated with abnormalities of this protein.

Yes, Hereditary Angioedema is an inherited disorder, usually passed down from one generation to the next.

Yes, the functional activity of C1 Esterase Inhibitor can vary, and in some individuals with hereditary angioedema, it may change over time.

The complement system is a part of the immune system that enhances the ability of antibodies and phagocytes to clear microbes and damaged cells, promote inflammation, and attack the pathogen's cell membrane.

There is no direct evidence to suggest that lifestyle changes can significantly impact C1 Esterase Inhibitor levels. However, a healthy lifestyle can contribute to overall immune system health.

The risks associated with the C1 Esterase Inhibitor - Functional test are minimal and similar to those of a standard blood draw, including bruising, infection, or slight pain at the site of the needle insertion.

Understanding the function of C1 Esterase Inhibitor is critical in the diagnosis and management of hereditary angioedema and other related conditions. This test is a valuable tool for both patients and doctors in evaluating the activity of this important protein and managing conditions that arise due to its deficiency or dysfunction.

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  • 5KM from Shaikpet