C1 Esterase Inhibitor - Functional Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No special preparation is required for this test.

₹ 4100


C1 Esterase Inhibitor, often abbreviated as C1-INH, is a protein found in the blood that plays a critical role in regulating the activation of certain components of the immune system. The functional C1 Esterase Inhibitor test is designed to assess the functional activity of this protein. This is important because certain disorders can result from the deficiency or malfunction of C1 Esterase Inhibitor, such as hereditary angioedema (HAE), which is a rare genetic disorder characterized by episodes of severe swelling in different parts of the body.

Test Name C1 Esterase Inhibitor - Functional (C1 Inactivator - Functional)
Sample Type Blood
Preparations Required No special preparation is required for this test.
Report Time 4 days
Price in Hyderabad ₹ 4100

What is C1 Esterase Inhibitor?

C1 Esterase Inhibitor is a protein in the blood that helps control inflammation and acts as a regulator of the complement and contact systems, both part of the immune response.

Why is the C1 Esterase Inhibitor - Functional test important?

This test is important for diagnosing conditions such as hereditary angioedema, where a deficiency or dysfunction of C1 Esterase Inhibitor can cause severe, recurrent swelling episodes. The test helps determine if the protein is present and functioning properly.

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What is Hereditary Angioedema (HAE)?

Hereditary Angioedema is a rare genetic disorder characterized by episodes of severe swelling, often affecting the face, extremities, airways, and intestinal tract. It is caused by a deficiency or malfunction of the C1 Esterase Inhibitor protein.

What does it mean if C1 Esterase Inhibitor is low or not functioning properly?

Low or non-functional C1 Esterase Inhibitor can lead to excessive activation of the complement system, resulting in recurrent episodes of angioedema, which is marked by severe swelling in different parts of the body.

How is the C1 Esterase Inhibitor - Functional test performed?

The test is performed using a blood sample. A healthcare professional will draw blood from a vein, usually in your arm, and the sample will be sent to a laboratory for analysis.

How can I prepare for this test?

No special preparation is needed for the C1 Esterase Inhibitor - Functional test. However, you should inform your doctor of any medications or supplements you are taking, as some can affect the test results.

What are the normal values for C1 Esterase Inhibitor - Functional?

Normal values can vary among different laboratories, but generally, the functional activity of C1 Esterase Inhibitor is expected to be within the range of 70-130% of normal.

Can C1 Esterase Inhibitor deficiency be treated?

Yes, treatment options for conditions caused by C1 Esterase Inhibitor deficiency, such as hereditary angioedema, include medications that replace the missing or non-functional protein, and medications that reduce swelling.

Which doctor should I consult if my C1 Esterase Inhibitor levels are abnormal?

You should consult an immunologist or allergist if your C1 Esterase Inhibitor levels are abnormal as these specialists have experience in managing disorders related to the immune system.

Is Hereditary Angioedema the only condition related to C1 Esterase Inhibitor?

No, while Hereditary Angioedema is the most common condition associated with C1 Esterase Inhibitor deficiency, there are other conditions and factors which may also be associated with abnormalities of this protein.

Can C1 Esterase Inhibitor deficiency be inherited?

Yes, Hereditary Angioedema is an inherited disorder, usually passed down from one generation to the next.

Can the functional activity of C1 Esterase Inhibitor change over time?

Yes, the functional activity of C1 Esterase Inhibitor can vary, and in some individuals with hereditary angioedema, it may change over time.

What is the complement system?

The complement system is a part of the immune system that enhances the ability of antibodies and phagocytes to clear microbes and damaged cells, promote inflammation, and attack the pathogen's cell membrane.

Can lifestyle changes impact C1 Esterase Inhibitor levels?

There is no direct evidence to suggest that lifestyle changes can significantly impact C1 Esterase Inhibitor levels. However, a healthy lifestyle can contribute to overall immune system health.

Are there any risks associated with this test?

The risks associated with the C1 Esterase Inhibitor - Functional test are minimal and similar to those of a standard blood draw, including bruising, infection, or slight pain at the site of the needle insertion.

Understanding the function of C1 Esterase Inhibitor is critical in the diagnosis and management of hereditary angioedema and other related conditions. This test is a valuable tool for both patients and doctors in evaluating the activity of this important protein and managing conditions that arise due to its deficiency or dysfunction.

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