c-Kit Mutation (GIST) - Tissue

The c-Kit Mutation (GIST) - Tissue test identifies mutations in the c-Kit gene in tissue samples. This gene produces a protein that sends signals inside cells, playing a key role in cell growth and division. Mutations in this gene are often associated with a type of cancer called gastrointestinal stromal tumors (GISTs). This test plays a critical role in the diagnosis and treatment of GISTs.

• Test Name c-Kit Mutation (GIST) - Tissue
• Sample Type paraffin block
• Preparations Required No special preparation, fasting or water consumption restrictions are required prior to the test.
• Report Time 10 days

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Home Sample Collection Process

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Book your convenient slot

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Sample Collection by Phlebotomist

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Reporting of the sample at lab

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Frequently Asked Questions

What is the c-Kit Mutation (GIST) - Tissue test?

The c-Kit Mutation (GIST) - Tissue test is a genetic test that identifies mutations in the c-Kit gene in tissue samples. These mutations are often linked to gastrointestinal stromal tumors (GISTs).

Why might I need this test?

This test may be recommended if you've been diagnosed with a gastrointestinal stromal tumor (GIST) or if you exhibit symptoms of this condition. The results can guide your treatment plan.

How is this test performed?

The test is performed on a tissue sample, typically obtained through a biopsy of the tumor.

What do the test results mean?

If a c-Kit mutation is detected, it suggests that your GIST may respond to certain targeted therapies. If no mutation is found, other treatments may be necessary.

How should I prepare for this test?

No special preparation is needed for this test. However, you should inform your doctor of any medications or supplements you're taking, as these may affect the results

What are the risks associated with this test?

The risks associated with this test are minimal and mostly related to the biopsy procedure used to obtain the tissue sample, which can include pain, infection, and bleeding.

What type of doctor should I see if my test results are abnormal?

If your test results are abnormal, consult an oncologist, a doctor who specializes in cancer treatment.

What treatment options are available if my test results are abnormal?

If a c-Kit mutation is found, targeted therapies, such as tyrosine kinase inhibitors, may be an effective treatment option.

Can other factors affect the results of this test?

Yes, certain medications and other medical conditions can affect the accuracy of this test. Discuss all of your health conditions and medications with your doctor prior to the test.

Is fasting required for this test?

No, fasting is not required before this test.

What are the normal values for this test?

Normal results would show no mutation in the c-Kit gene. However, the interpretation of results should always be done in conjunction with your symptoms, medical history, and other diagnostic tests.

What does an abnormal result mean?

An abnormal result, i.e., the presence of a c-Kit mutation, suggests that your GIST might respond to certain types of targeted therapies.

How often should I get this test?

The frequency of this test will depend on your doctor's recommendations, based on your diagnosis, treatment plan, and response to therapy.

What precautions should I take after the test?

No specific precautions are needed after the test. However, it's important to discuss your results with your doctor, who can guide you on the next steps of your treatment plan.

Are there any side effects of this test?

There are no direct side effects associated with the test, but the biopsy procedure to obtain the tissue sample can cause temporary discomfort or bruising.

Can I take this test at home?

No, this test requires a tissue sample from a biopsy procedure, which should be performed by a healthcare professional in a clinical setting.

What are the modifiable factors affecting the test results?

There are no modifiable factors that significantly impact the results of this test as the presence or absence of c-Kit mutations is primarily determined by genetics.

What are the nonmodifiable factors affecting the test results?

The nonmodifiable factors that affect the results of this test are primarily genetic. Your genetic makeup determines whether or not you have a c-Kit mutation.

What should I do if my test results are abnormal?

If your test results are abnormal, consult your doctor to discuss the appropriate treatment options.

Can medications affect my test results?

Certain medications might potentially interfere with the results of this test. Be sure to discuss all medications and supplements you're currently taking with your doctor.

This test provides valuable information that can guide the diagnosis and treatment of gastrointestinal stromal tumors (GISTs). Understanding your test results can aid you and your doctor in making informed decisions about your healthcare.