Bence Jones protein (BJ protein) test is a valuable medical examination used to detect and monitor a
specific type of protein known as Bence Jones proteins in urine. This type of protein is most
commonly associated with a type of cancer called multiple myeloma, a malignancy of plasma cells that
reside in the bone marrow.
Test Name Bence Jones Protein (BJ Protein) Test
Sample Type Urine
Preparations Required No special preparation is necessary for this test
Report Time 4 days
Multiple myeloma is a disorder characterized by the production of abnormal plasma cells. These
cancerous cells disrupt the normal balance of cells within the bone marrow, causing a range of
complications, including anemia, bone damage, kidney failure, and impaired immune functions. One of
the significant diagnostic hallmarks of multiple myeloma is the production of abnormal antibodies or
parts of antibodies, including Bence Jones proteins.
Bence Jones proteins are light chains of antibodies that are produced in excess by the abnormal
plasma cells in conditions such as multiple myeloma. These proteins are too small to be effectively
filtered by the kidneys, resulting in their presence in the urine, which can be detected through the
Bence Jones protein test.
The Bence Jones protein test is a urine test that requires a 24-hour urine sample. It is an
essential test that helps diagnose multiple myeloma and monitor the disease's progression and
response to treatment. The test can identify Bence Jones proteins even in small amounts, making it
highly sensitive and vital in early detection
Moreover, the quantity of Bence Jones proteins in the urine provides a useful marker of disease
activity. A high level of these proteins usually indicates a large number of cancerous plasma cells,
a significant disease burden, and an increased risk of kidney damage.
Home Sample Collection Process
1
Book your convenient slot
2
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
4
Download Reports
Frequently Asked Questions
This test measures the amount of Bence Jones proteins, a type of light chain
antibody, in your urine. It is primarily used to help diagnose and monitor
multiple myeloma, a type of blood cancer.
This test is important because it helps to detect multiple myeloma, a type of
cancer that affects plasma cells in the bone marrow. The presence of Bence Jones
proteins in the urine is a common sign of this disease.
The test requires a 24-hour urine sample. The sample is then analyzed in a
laboratory for the presence of Bence Jones proteins.
No special preparation is required for this test. However, you should ensure to
collect all urine produced in a 24-hour period.
If Bence Jones proteins are found in your urine, it may indicate multiple
myeloma or another related condition. The level of these proteins can also help
to determine the extent of the disease and how well treatment is working.
The frequency of the test depends on the individual's condition. It is typically
performed at diagnosis and at regular intervals during treatment to monitor
response and disease progression.
While the urine sample collection can be done at home, the sample must be
analyzed in a specialized laboratory.
If your test results are abnormal, you should consult with a hematologist, a
doctor who specializes in blood diseases and disorders.
The Bence Jones protein test is a crucial investigation tool in diagnosing and
managing multiple myeloma. Understanding this test and its significance is a
vital part of managing this condition. As always, communication with your
healthcare provider is key in understanding your health condition and its
management.
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