Asparagine - Quantitative - Plasma

Asparagine is an amino acid, which is a building block of proteins. The body uses it to help make and maintain proteins that are necessary for the functioning and structure of the body's cells, tissues, and organs. Additionally, asparagine plays a role in the production of other amino acids and is involved in certain metabolic processes.

Asparagine is crucial for brain development and functioning. It helps maintain the balance of chemicals in the brain and is involved in the synthesis of neurotransmitters. Asparagine also plays a role in the urea cycle, which is the process by which the body eliminates ammonia, a toxic product of protein metabolism.

The test is performed to measure the levels of asparagine in the plasma. This can be important in assessing the nutritional status of an individual, especially in those with metabolic disorders. It is also used in the monitoring and diagnosis of conditions such as Asparagine Synthetase Deficiency, a rare genetic disorder that leads to a lack of asparagine and affects brain development.

Excessively high levels of asparagine, though rare, can be associated with health issues. For example, some studies suggest that high asparagine levels might be linked to the spread of certain cancers.

Eating a balanced diet with adequate protein can help maintain normal asparagine levels. In cases of deficiency due to metabolic disorders, a doctor might recommend dietary supplements or other interventions.

Yes, there are medications such as Asparaginase, which is used in the treatment of acute lymphoblastic leukemia, that can affect asparagine levels in the blood.

If your test shows abnormal levels of asparagine, it is important to consult a doctor to understand the underlying cause and receive appropriate guidance and treatment if necessary.

For most people, asparagine supplementation is not necessary as the body can produce it and it is also obtained through diet. However, in cases of metabolic disorders affecting asparagine synthesis, supplementation might be needed under a doctor’s supervision.

Yes, Asparagine Synthetase Deficiency is a rare genetic disorder associated with low levels of asparagine. This condition affects brain development and function.

There is limited data on this, but as asparagine is important for protein synthesis and metabolic processes, it is assumed to be important for fetal development. Pregnant women should ensure a balanced diet or follow a doctor’s advice regarding nutrition.

A deficiency in asparagine can lead to symptoms such as:

• Developmental delays
• Intellectual disabilities
• Seizures
• Microcephaly (small head size)
• Movement disorders

Asparagine is found in various foods, including:

• Dairy products
• Beef
• Poultry
• Eggs
• Fish
• Seeds
• Legumes
• Whole grains
• Nuts

For issues related to asparagine levels, it is recommended to consult a general physician initially, who may then refer you to a specialist such as a nutritionist, endocrinologist, or geneticist depending on the underlying cause.

Asparagine is an essential amino acid vital for brain function and the synthesis of proteins and other amino acids. The Asparagine - Quantitative - Plasma test measures its levels in the plasma, and can be crucial in evaluating nutritional status, diagnosing metabolic disorders, or monitoring certain treatments. It is important to consult a doctor for interpretation of the results and guidance on managing any issues related to asparagine levels.