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Lab Test

Anti-Saccharomyces Cerevisiae (ASCA) IgG Antibody Test

Anti-Saccharomyces Cerevisiae Antibodies (ASCA) are antibodies that are directed against certain proteins found in yeast, primarily Saccharomyces cerevisiae, commonly known as baker’s or brewer’s yeast. There are different types of ASCA antibodies, including IgG and IgA. The presence of ASCA IgG antibodies in blood can be an important marker for Crohn's disease, which is a type of inflammatory bowel disease (IBD).


Crohn's disease causes chronic inflammation of the gastrointestinal tract. It can affect any part of it but most often affects the small intestine. There’s no known cure for Crohn's disease, but therapies can greatly reduce its signs and symptoms and even bring about long-term remission.

  • Profile Name: Anti-Saccharomyces Cerevisiae (ASCA) IgG Antibody Test
  • Sample Type: Blood
  • Preparations Required: No special preparation is required for this test.
  • Report Time: 6 hours

What is the ASCA IgG Antibody Test used for?

The ASCA IgG Antibody Test is primarily used to help in diagnosing Crohn’s disease. It is used in conjunction with other tests and clinical evaluation as a part of the diagnostic process.

How is the ASCA IgG Antibody Test performed?

The test is performed by drawing a blood sample from the patient. This blood sample is then sent to a laboratory for analysis to check for the presence of ASCA IgG antibodies.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Download Reports
Frequently Asked Questions

No, fasting is not necessary for the ASCA IgG Antibody Test.

A positive ASCA IgG test indicates the presence of IgG antibodies against Saccharomyces cerevisiae. This is often associated with Crohn’s disease, but not everyone with a positive test has this condition.

While a positive ASCA IgG test is most commonly associated with Crohn’s disease, other conditions such as other forms of inflammatory bowel disease and sometimes celiac disease can also cause a positive result.

Yes, it is possible to have Crohn’s disease with a negative ASCA IgG test, as not every patient with Crohn's disease will have these antibodies.

The ASCA IgG test can be used alongside other blood tests, stool tests, and imaging studies to form a more comprehensive view of a patient's gastrointestinal health.

ASCA IgG and IgA are different types of antibodies. IgG antibodies are more common and often found in the blood, while IgA antibodies are often associated with mucosal surfaces.

Yes, it is possible for a person without any symptoms to have a positive ASCA IgG test, although it is more common among those with symptoms of inflammatory bowel diseases.

No, while Crohn’s disease is the most common cause of a positive ASCA IgG test, other forms of IBD can sometimes cause a positive result as well.

Treatment for Crohn’s disease often involves medications to reduce inflammation in the gut, changes in diet, and sometimes surgery to remove damaged sections of the gastrointestinal tract.

The frequency of testing varies depending on the severity of the disease and the treatment plan. Your doctor will provide guidance on how often you should be tested.

If you have a positive ASCA IgG test, it is important to consult a gastroenterologist for further evaluation and to discuss potential next steps in diagnosis and treatment.

Factors that can affect the levels of ASCA IgG include genetic predisposition, immune system activity, and environmental factors such as diet.

If you have an abnormal ASCA IgG value, you should consult a gastroenterologist, who specializes in disorders of the digestive system.

Understanding the role of the Anti-Saccharomyces Cerevisiae (ASCA) IgG Antibody Test in the diagnostic process of Crohn’s disease is essential for patients undergoing evaluation for gastrointestinal issues. Collaborating closely with your doctor to understand the results and formulate a comprehensive plan for managing and treating any underlying conditions that are discovered is vital. This test is a valuable tool that, when used in conjunction with other diagnostic measures, can provide significant insights into a patient's gastrointestinal health.

SACCHAROMYCES CEREVISIAE ANTIBODY (ASCA) IGG, SERUM
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