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Anti-Parietal Cell Antibodies (APCA) Test via IFA with Titer

Anti-Parietal Cell Antibodies (APCA) Test via IFA with Titer

Anti-Parietal Cell Antibodies (APCA) are antibodies produced by the immune system that mistakenly target and attack the parietal cells in the stomach. The parietal cells are responsible for producing intrinsic factor and stomach acid. Intrinsic factor is crucial for the absorption of vitamin B12, which is essential for the production of red blood cells and proper neurological function. The APCA test, performed through Indirect Immunofluorescence Assay (IFA) with titer, measures the presence and concentration of these antibodies in the blood. This test is commonly used in the diagnosis and monitoring of autoimmune conditions such as pernicious anemia.

Pernicious anemia is a type of anemia that occurs when there is a lack of vitamin B12 absorption due to the body's inability to produce intrinsic factor. As the production of intrinsic factor is impeded by the presence of anti-parietal cell antibodies, the body cannot effectively absorb vitamin B12 from the diet. This leads to anemia, fatigue, weakness, and neurological symptoms.

  • Test Name: Anti-Parietal Cell Antibodies (APCA) Test via IFA with Titer
  • Sample Type: Blood
  • Preparations Required :No special preparation is needed for this test.
  • Report Time : 24 hours

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

A doctor might order the APCA test if a patient is showing signs of anemia, such as fatigue, weakness, or difficulty concentrating, especially if there is a suspicion of pernicious anemia or other autoimmune disorders affecting the stomach.

The APCA test is performed using a blood sample, typically drawn from a vein in the arm. The sample is then analyzed in a laboratory through Indirect Immunofluorescence Assay (IFA) with titer to detect and measure the presence of anti-parietal cell antibodies.

A positive APCA test indicates the presence of anti-parietal cell antibodies in the blood. This can be a sign of pernicious anemia or other autoimmune conditions affecting the stomach.

The risks associated with the APCA test are minimal and are similar to those associated with a routine blood draw. These may include slight pain or bruising at the site of needle insertion, or, in very rare cases, infection.

A positive result for anti-parietal cell antibodies is suggestive of pernicious anemia but is not conclusive on its own. Further tests, such as vitamin B12 levels and a complete blood count, may be necessary for a definitive diagnosis.

Indirect Immunofluorescence Assay (IFA) with titer is a laboratory technique used to detect and measure the concentration of antibodies in the blood. In the APCA test, it helps determine not only the presence but also the amount of anti-parietal cell antibodies, which can be useful for diagnosis and monitoring purposes.

blood? APCA levels are usually not influenced by lifestyle changes. They are antibodies produced by the immune system. If elevated levels are due to an autoimmune disorder, a doctor might prescribe medication to manage the condition.

No, the APCA test is not a part of routine health check-ups. It is ordered specifically when there is a suspicion of pernicious anemia or other autoimmune conditions affecting the stomach.

Yes, the APCA test can be performed on individuals of any age, including children, if there is a clinical suspicion of an autoimmune disorder affecting the stomach.

Certain medications, particularly those that suppress the immune system, may affect the results of an APCA test. It's important to inform your doctor of any medications you are taking.

Along with the APCA test, a doctor might order vitamin B12 levels, complete blood count, intrinsic factor antibodies, and other tests to assess the overall health and rule out or confirm the diagnosis of pernicious anemia.

No, APCA levels are not directly affected by diet. However, dietary habits can influence the condition that leads to the production of APCAs, such as vitamin B12 intake in the case of pernicious anemia.

APCA levels? Symptoms may include fatigue, weakness, difficulty concentrating, numbness or tingling in the extremities, difficulty maintaining balance, and memory problems.

abnormal? If your APCA levels are abnormal, it is advisable to consult a hematologist or a gastroenterologist for further evaluation and management.

The frequency of testing for APCA levels should be determined by your doctor based on your health status, symptoms, and any underlying conditions.

Understanding the significance of anti-parietal cell antibodies and their role in your health is crucial, especially for those with autoimmune disorders or anemia. By staying informed and maintaining regular communication with your doctor, you can actively participate in the management and care of your health.

Anti Parietal cell Antibodies (APCA) - IFA with titer
₹ 3000
Schedule Test in Your Available Time
Locations Near You in Hyderabad
  • 4KM from Madhapur
  • 3KM from Banjara Hills
  • 1.9KM from Yusufguda
  • 3KM from Madhura Nagar
  • 5KM from Shaikpet