Anti Mitochondrial Antibody - IFA with Reflex Titers Test - Price - Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : There are no specific instructions required for this test.

₹ 2900


The Anti Mitochondrial Antibody (AMA) - IFA with Reflex Titers test is a crucial diagnostic tool for primary biliary cholangitis (PBC), a chronic liver disease. AMA is an antibody produced when the body's immune system mistakenly attacks the cells of the liver's small bile ducts. This test not only identifies the presence of AMA but also quantifies their levels, known as titers, in the bloodstream.

This test holds significant importance in diagnosing PBC because AMAs are present in about 95% of individuals with this disease. Nonetheless, a smaller percentage of people with other liver or autoimmune diseases and even some healthy individuals may also have AMAs. Therefore, the test is often used along with other clinical findings and tests to establish a diagnosis.

Test Name Anti Mitochondrial Antibody (AMA) - IFA with Reflex Titers
Sample Type Blood
Preparations Required There are no specific instructions required for this test.
Report Time 24 hours
Price ₹ 2900

Why is the Anti Mitochondrial Antibody test with reflex titers important?

The AMA test with reflex titers is essential for diagnosing primary biliary cholangitis. It not only detects the presence of these antibodies but also measures their levels, offering valuable insight into the disease's progression and severity.

Is fasting required for the Anti Mitochondrial Antibody test?

No, fasting is not required for this test.

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Is there any specific preparation required for the Anti Mitochondrial Antibody test?

There is no specific preparation necessary for the AMA test. However, you should inform your healthcare provider about any medications, vitamins, or supplements you're currently taking.

When should I get the Anti Mitochondrial Antibody test?

Your healthcare provider might recommend this test if you exhibit symptoms indicative of liver disease, such as fatigue, itchy skin, jaundice (yellowing of the skin or eyes), or discomfort in the upper right abdomen. You may also need this test if your liver function tests are abnormal.

What does the Anti Mitochondrial Antibody test measure?

The AMA test with reflex titers measures the presence and quantity of anti-mitochondrial antibodies in your blood. These are autoantibodies produced by your immune system that mistakenly attack the cells of the liver's small bile ducts.

How frequently should I get tested?

The frequency of this test will depend on your specific health condition and your healthcare provider's advice. If you have PBC or another autoimmune liver disease, regular monitoring might be necessary to assess your condition and the effectiveness of your treatment.

What are the normal values for the Anti Mitochondrial Antibody test?

Normally, AMA should not be present in the bloodstream. A positive result indicates the presence of these antibodies, which could suggest an autoimmune liver disease, such as PBC.

Are there any precautions I need to take?

There are no specific precautions required for this test. However, if your results show elevated AMA levels, it's crucial to follow your healthcare provider's advice regarding managing your condition.

What factors can affect the levels of Anti Mitochondrial Antibodies?

Several factors can influence AMA test results, including certain medical conditions and medications. It's important to discuss your current health status and any medications you're taking with your healthcare provider before the test.

Which doctor should I consult if my Anti Mitochondrial Antibody test comes back positive?

If your AMA test comes back positive, you should consult a hepatologist or a gastroenterologist. These specialists focus on the liver and digestive system, respectively, and can provide appropriate diagnosis and treatment options.

Can elevated Anti Mitochondrial Antibodies indicate conditions other than PBC?

While elevated AMA levels are commonly associated with PBC, they can also be detected in individuals with other liver and autoimmune diseases, albeit less commonly. Some healthy individuals may also have AMAs, but this occurrence is rare.

Are Anti Mitochondrial Antibodies hereditary?

The presence of AMAs and PBC might have a genetic link as they tend to occur more frequently in certain families. However, the exact cause of these conditions is still unknown and is believed to be a combination of genetic predisposition and environmental factors.

Can the Anti Mitochondrial Antibody test determine the severity of my disease?

While the AMA test with reflex titers provides information about the presence and quantity of these antibodies, it does not directly determine disease severity. Your healthcare provider will assess your condition based on a variety of factors, including symptoms, medical history, and additional diagnostic tests.

Can healthy individuals have abnormal Anti Mitochondrial Antibody levels?

It is rare, but some healthy individuals may have AMAs in their blood. If you are asymptomatic and test positive for AMAs, it is essential to consult with your healthcare provider for further evaluations and regular monitoring.

How are the results of the Anti Mitochondrial Antibody test interpreted?

Your healthcare provider will interpret the results of the AMA test in conjunction with your symptoms, medical history, and other relevant tests. A positive result could indicate an autoimmune liver disease like PBC, but additional tests may be required to confirm the diagnosis.

Can a negative AMA test rule out PBC?

A negative result can make PBC less likely, but it does not completely rule it out. Some individuals with PBC may not have detectable AMA levels. If PBC is strongly suspected, other tests may be recommended to confirm the diagnosis.

How reliable is the Anti Mitochondrial Antibody test with reflex titers?

The AMA test with reflex titers is considered highly reliable for diagnosing PBC. These antibodies are present in about 95% of individuals with PBC. However, the test's results should always be interpreted in the context of other clinical findings for an accurate diagnosis.

What other tests might be ordered alongside an AMA test?

If the AMA test result is positive, your healthcare provider might order additional tests to assess your disease's extent. These can include a complete blood count, liver function tests, cholesterol tests, and imaging studies of the liver and bile ducts.

Can lifestyle changes affect the levels of Anti Mitochondrial Antibodies?

Lifestyle changes do not directly affect AMA levels. However, maintaining a healthy lifestyle can help manage symptoms of conditions related to high AMA levels, such as PBC.

Is there a cure for conditions related to elevated Anti Mitochondrial Antibodies?

Currently, there is no cure for PBC. However, treatments are available to manage symptoms and slow disease progression. These treatments can include medications, lifestyle changes, and in severe cases, liver transplantation.

Understanding your Anti Mitochondrial Antibody test results is a crucial step in diagnosing and managing diseases like PBC. It can help you and your healthcare provider make informed decisions about your health and well-being. Stay informed, ask questions, and always prioritize your health.

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