Anti-ds-DNA Antibody IFA with Reflex Titers Test - Price | Sprint Diagnostics Hyderabad

Patient Preparing : No special preparations are necessary for the Anti-ds-DNA Antibody test.

₹ 2000


The Anti-ds-DNA Antibody test, performed using an indirect immunofluorescence assay (IFA) with reflex titers, checks for the presence and quantity of anti-double-stranded DNA (anti-ds-DNA) antibodies in the blood. These autoantibodies often emerge in individuals with certain autoimmune disorders, notably systemic lupus erythematosus (SLE).

Autoantibodies like anti-ds-DNA are a subset of antinuclear antibodies (ANA) that mistakenly attack the body's own cells. In the context of the Anti-ds-DNA test, a positive result can affirm the diagnosis of SLE. Furthermore, the reflex titers allow for a more precise evaluation of antibody levels, helping to monitor disease progression and the effectiveness of therapy.

Test Name Anti-ds-DNA Antibody - IFA with Reflex Titers
Sample Type Blood
Preparations Required No special preparations are necessary for the Anti-ds-DNA Antibody test.
Report Time 24 Hours
Price ₹ 2000

Why is the Anti-ds-DNA test important?

The Anti-ds-DNA test is crucial for diagnosing and managing systemic lupus erythematosus (SLE), a complex autoimmune disease. The detection of these autoantibodies enables early diagnosis and timely treatment of SLE, potentially preventing severe complications such as kidney damage.

Is fasting required for the Anti-ds-DNA test?

No, fasting is not required for the Anti-ds-DNA test. You can maintain your usual diet and fluid intake prior to the test.

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Do I need to prepare in any specific way for the Anti-ds-DNA test?

There are no specific preparations required for the Anti-ds-DNA test. However, you should inform your healthcare provider about any medications or supplements you're currently taking, as they may interfere with the results.

When should I take the Anti-ds-DNA test?

Your doctor might recommend the Anti-ds-DNA test if you exhibit symptoms suggestive of SLE. These can include fatigue, joint pain, skin rash, unexplained fever, hair loss, mouth or nose ulcers, or swollen glands.

What does the Anti-ds-DNA test measure?

The Anti-ds-DNA test measures the presence and quantity of anti-ds-DNA antibodies in your blood. High levels of these antibodies are strongly associated with SLE, particularly in active disease states.

How often should I take the Anti-ds-DNA test?

If you have been diagnosed with SLE, your doctor may recommend regular testing to monitor your condition, particularly during flare-ups or to evaluate the response to treatment. The frequency of testing is individualized based on your specific circumstances and disease progression.

What are the normal values for the Anti-ds-DNA test?

A negative result is considered normal for the Anti-ds-DNA test. However, the specific numerical values for "positive" or "negative" can vary depending on the laboratory performing the test.

Are there any precautions I should take?

There are no specific precautions for the Anti-ds-DNA test itself. However, if your results show the presence of anti-ds-DNA antibodies, your doctor will guide you on the necessary treatments and precautions to manage your condition.

What factors can affect the results of the Anti-ds-DNA test?

The presence and levels of anti-ds-DNA antibodies can be influenced by disease activity in SLE. Other factors, such as certain medications and the presence of other autoimmune diseases, can also potentially affect the test results.

Which doctor should I consult if my Anti-ds-DNA test is positive?

If your Anti-ds-DNA test is positive, you should consult a rheumatologist, a specialist in autoimmune diseases and conditions affecting the joints, muscles, and bones.

Can high anti-ds-DNA levels indicate any other conditions?

While high levels of anti-ds-DNA antibodies are most commonly associated with SLE, they can also be present in other autoimmune conditions. However, their presence is considered a hallmark of SLE, particularly in those with active disease.

Can anti-ds-DNA levels be hereditary?

There is no direct hereditary pattern for anti-ds-DNA levels. However, susceptibility to developing SLE, the condition most often associated with these antibodies, does have a genetic component.

Can the Anti-ds-DNA test determine the severity of my condition?

High levels of anti-ds-DNA antibodies can indicate a more active or severe disease state in individuals with SLE, especially if kidney involvement is present. By providing a quantitative measure of these antibodies, the Anti-ds-DNA test with reflex titers can help gauge the severity of the disease.

Can healthy individuals have abnormal anti-ds-DNA levels?

It's unusual for healthy individuals to have high levels of anti-ds-DNA antibodies. These antibodies are typically present in those with autoimmune conditions like SLE.

How are the results of the Anti-ds-DNA test interpreted?

Your healthcare provider should interpret your test results, taking into account your symptoms, medical history, and other test results. Elevated levels of anti-ds-DNA antibodies, especially in combination with positive ANA test results, strongly suggest a diagnosis of SLE.

Understanding the significance of the Anti-ds-DNA test is crucial for those with suspected or confirmed SLE. This knowledge empowers patients to actively participate in managing their health, guided by their healthcare provider's expertise. Regular monitoring and appropriate treatment can significantly improve the quality of life in individuals with SLE.

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