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Anti-Aquaporin-4 / NMO Antibodies

Anti-Aquaporin-4 antibodies, also known as NMO (Neuromyelitis Optica) antibodies, are autoantibodies that target a specific protein called aquaporin-4 found on the surface of cells in the brain and spinal cord. Neuromyelitis Optica, also known as Devic's disease, is an autoimmune disorder in which the immune system attacks the optic nerves and spinal cord. This can cause symptoms such as vision loss, muscle weakness, and impaired coordination. The Anti-Aquaporin-4 / NMO Antibodies test is used to detect the presence of these antibodies in the blood, helping in the diagnosis and management of Neuromyelitis Optica.


  • Test NameAnti-Aquaporin-4 / NMO Antibodies (Neuromyelitis Optica Antibodies) Test
  • Sample TypeBlood (Serum)
  • Preparations RequiredNo specific preparation is required for this test.
  • Report Time6 hours

Home Sample Collection Process
1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

The Anti-Aquaporin-4 / NMO Antibodies test is a blood test that detects the presence of antibodies against the aquaporin-4 protein, which is found on cells in the brain and spinal cord. The presence of these antibodies is associated with Neuromyelitis Optica, an autoimmune disorder.

Symptoms of Neuromyelitis Optica include vision loss, pain in the eyes, muscle weakness, impaired coordination, and, in severe cases, paralysis. These symptoms occur due to inflammation and damage to the optic nerves and spinal cord.

This test is essential for diagnosing Neuromyelitis Optica, distinguishing it from other disorders with similar symptoms such as multiple sclerosis, and guiding appropriate treatment strategies. Early diagnosis and treatment can help manage symptoms and prevent severe complications.

A healthcare professional will collect a blood sample from a vein in your arm using a needle. The procedure is relatively quick and may cause only minor discomfort.

A positive result indicates the presence of Anti-Aquaporin-4 antibodies in the blood, suggesting a diagnosis of Neuromyelitis Optica. However, clinical evaluation and additional testing may be needed to confirm the diagnosis.

Yes, a small percentage of individuals with Neuromyelitis Optica do not have detectable Anti-Aquaporin-4 antibodies. These cases are often referred to as seronegative NMO.

Treatment for Neuromyelitis Optica includes medications to suppress the immune system and manage symptoms, as well as physical therapy to improve mobility and muscle strength.

Neuromyelitis Optica is not typically considered a hereditary condition, but certain genetic factors may increase the susceptibility to developing the disorder.

There is currently no cure for Neuromyelitis Optica, but treatments can help manage symptoms and reduce the frequency and severity of relapses.

You should consult a neurologist if you have abnormal Anti-Aquaporin-4 / NMO antibodies, as this is suggestive of Neuromyelitis Optica, which is a neurological disorder.

There are no known modifiable factors that can affect the levels of Anti-Aquaporin-4 antibodies, but treatment with immunosuppressive medication may reduce antibody levels and help manage the symptoms of the disease.

The frequency of testing for Anti-Aquaporin-4 / NMO antibodies depends on your clinical symptoms, the doctor's assessment, and the management plan for Neuromyelitis Optica.

Yes, complications of Neuromyelitis Optica can include permanent vision loss, muscle weakness, bladder or bowel dysfunction, and, in severe cases, respiratory failure.

There is no direct evidence that diet or lifestyle changes affect the course of Neuromyelitis Optica, but maintaining a healthy lifestyle can have general benefits for overall health.

The prognosis for individuals with Neuromyelitis Optica varies. With appropriate treatment, many people can manage their symptoms effectively, though the condition can be disabling or life-threatening in severe cases.

Understanding the role of Anti-Aquaporin-4 / NMO antibodies in the diagnosis of Neuromyelitis Optica is crucial for patients suspected of having this autoimmune disorder. Timely diagnosis and appropriate management can make a significant difference in the quality of life for individuals with this condition. Always consult your doctor for professional advice and information regarding diagnosis and treatment options.

Anti-Aquaporin-4 / NMO Antibodies ( Neuromyelitis Optica Antibodies)
₹ 4500
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