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angiotensin-converting-enzyme-serum

Angiotensin Converting Enzyme (ACE) - Serum

The Angiotensin Converting Enzyme (ACE) test is a blood test that measures the amount of ACE in your blood. ACE is an enzyme that helps regulate blood pressure by converting a hormone called angiotensin I to a potent substance called angiotensin II. This test is typically used to help diagnose and monitor certain diseases, most notably sarcoidosis, a disease characterized by inflammation in various parts of the body, often affecting the lungs and lymph nodes.


  • Test Name Angiotensin Converting Enzyme (ACE) - Serum
  • Sample Type Blood
  • Preparations Required No special preparation is required for this test. However, do inform your doctor about any medications you're currently taking, as certain medications can interfere with the test results.
  • Report Time 6 hours

Besides sarcoidosis, elevated levels of ACE can be seen in a number of other conditions, including Gaucher's disease, hyperthyroidism, leprosy, amyloidosis, and lung cancer. In some cases, ACE levels can be low in conditions such as chronic liver disease, emphysema, or hypothyroidism. However, the primary use of the ACE test in clinical practice remains the diagnosis and monitoring of sarcoidosis.

Home Sample Collection Process

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Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
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Reporting of the sample at lab
Reporting of the sample at lab
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Frequently Asked Questions

An ACE test is a blood test that measures the level of ACE in your blood. ACE is an enzyme involved in regulating blood pressure, but its level can increase in certain medical conditions, particularly sarcoidosis.

An ACE test is primarily ordered to help diagnose sarcoidosis, especially in cases where the symptoms are unclear or when the results of other tests are inconclusive. It can also be used to monitor the progress of the disease and the effectiveness of treatment.

The test is performed using a blood sample that is typically drawn from a vein in your arm.

No special preparation is required for the ACE test. However, you should inform your doctor about any medications you're taking, as some drugs can affect the test results.

High levels of ACE may suggest sarcoidosis or other conditions such as Gaucher's disease or certain forms of cancer. Low levels may indicate conditions like chronic liver disease or emphysema. However, ACE levels can also be normal in many people with these conditions, so this test is not definitive on its own.

The frequency of testing depends on your health status and your doctor's recommendations. If you are being monitored for sarcoidosis, your doctor will advise on the frequency of testing.

If your ACE levels are abnormal, it would be advisable to consult a pulmonologist, as sarcoidosis commonly affects the lungs. However, the specialist may vary based on the organ system involved.

Certain medications, health conditions, and even the method of testing can affect your ACE levels. Make sure to inform your doctor about all your current medications and health conditions.

The risks associated with an ACE test are minimal and similar to those associated with any blood test. These may include slight pain, bruising, or bleeding at the injection site.

Yes, this test can be safely taken during pregnancy. However, as with any medical procedure, you should inform your doctor if you are pregnant.

While the ACE test can be a useful tool in diagnosing and monitoring sarcoidosis, it is not definitive on its own. A combination of medical history, symptoms, and various other tests are typically used to make a diagnosis.

No specific foods are known to significantly affect ACE levels. However, maintaining a healthy diet is always beneficial for overall health.

No, the ACE test requires a blood sample to be taken by a healthcare professional and analyzed in a laboratory.

Persistently high ACE levels despite treatment may indicate that the condition is not being effectively managed and may require a change in treatment strategy. This should be discussed with your doctor.

Yes, children can undergo this test if it's recommended by a healthcare professional.

The Angiotensin Converting Enzyme (ACE) test is a valuable tool in diagnosing and monitoring conditions like sarcoidosis. Despite its limitations, it is an essential part of a combination of tests used to make an accurate diagnosis. As always, interpreting the test results should be done by a qualified healthcare professional considering your overall health status and medical history. Regular follow-ups and adherence to treatment plans are essential for managing any health condition effectively.

ANGIOTENSIN CONVERTING ENZYME (ACE), SERUM
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